668478-79-3

Basic information

• Product Name: Benzenecarbothioamide, 3,5-dimethyl-
• CAS NO: 668478-79-3
• Molecular Formula: C9H11NS
• Molecular Weight: 165.259
• Mol File: 668478-79-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioamide, 3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioamide, 3,5-dimethyl-(668478-79-3)
• EPA Substance Registry System: Benzenecarbothioamide, 3,5-dimethyl-(668478-79-3)

Safety Data

• Hazardous Substances Data: 668478-79-3(Hazardous Substances Data)

Upstream product

• 22445-42-7 3,5-dimethylbenzonitrile 

Downstream Products

• 1013621-94-7 2-(3,5-dimethylphenyl)thiazole-4,5-dione 

Relevant articles and documents

Aerobic Visible-Light Induced Intermolecular S?N Bond Construction: Synthesis of 1,2,4-Thiadiazoles from Thioamides under Photosensitizer-Free Conditions

Aerobic visible-light induced intermolecular S?N bond construction has been achieved without the addition of photosensitizer, metal, or base. With this strategy, 1,2,4-thiadiazoles can be obtained from thioamides. Preliminary mechanistic investigation suggested that the excited state of thioamides undergoes a single-electron-transfer (SET) process to afford thioamidyl radicals, which can be further transformed into a 1,2,4-thiadiazole through desulfurization and oxidative cyclization. The reaction has good functional group tolerance and represents a green method for the construction of S?N bonds.