66849-37-4Relevant academic research and scientific papers
SYNTHESIS OF PYRIMIDINE DERIVATIVES BY REACTION OF PYRYLIUM SALTS WITH GUANIDINE AND COMPOUNDS OF THE GUANIDINE SERIES
Zvezdina, E. A.,Zhdanova, M. P.,Dorofeenko, G. N.
, p. 574 - 578 (1980)
2,4,6-Triphenylpyrylium perchlorate reacts with methylguanidine to give 1-methyl-2-amino-4,6-diphenylpyrimidinium perchlorate, which undergoes the Dimroth rearrangement to give 2-methylamino-4,6-diphenylpyrimidine. 2,4,6-Triarylpyrylium perchlorates react
Flow reactor approach for the facile and continuous synthesis of efficient Pd@Pt core-shell nanoparticles for acceptorless dehydrogenative synthesis of pyrimidines from alcohols and amidines
Poly, Sharmin Sultana,Hashiguchi, Yuta,Sultana, Asima,Nakamura, Isao,Shimizu, Ken-ichi,Yasumura, Shunsaku,Fujitani, Tadahiro
, (2021/04/23)
Carbon supported Pd@Pt core-shell nanoparticles catalyst was prepared in a flow reactor toachieve enhanced catalytic activities with low Pt loading for the acceptorless dehydrogenative synthesis of pyrimidines. Spectroscopic (XAS analysis) and microscopic (HAADF-STEM) techniques reveled that the core-shell structure was formed by the applied preparation method. The Pd@Pt/PVP (polyvinylpyrrolidone)/C catalyst showed the activity for the three component one pot synthesis of pyrimidines through a series of consecutive reactions including oxidation of alcohols, C[sbnd]C, and C[sbnd]N coupling, followed by heterocyclization and dehydrogenation employing various primary alcohols, secondary alcohols, and amidines. The reaction mechanism on Pd@Pt/PVP/C catalyst was explored by comparison with the control experiments.
