66892-28-2Relevant articles and documents
COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA
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Page/Page column 73, (2014/10/15)
The present invention provides aminohydantoin anti-malarial agents. In some embodiments, these agents have the property of functions of targeting malarial aspartic proteases while at the same time having low activity against human BACE. Methods of employing such agents are also provided.
A Mild and Efficient Method for the Preparation of Guanidines
Poss, Michael A.,Iwanowicz, Edwin,Reid, Joyce A.,Lin, James,Gu, Zhengxiang
, p. 5933 - 5936 (2007/10/02)
A mild and efficient method for the preparation of guanidines by reaction of an acylated thiourea with an amine followed by removal of the acyl groups(s) from the intermediate acylguanidine is reported.Key Words: acylguanidine, acylthiourea, guanidine, water soluble carbodiimide
N,N'-disubstituted guanidine high-potency sweeteners
Muller,Walters,DuBois
, p. 740 - 743 (2007/10/02)
The role and function of the aryl group in the highly potent trisubstituted guanidine sweeteners 7a-d was investigated. Four disubstituted guanidines, lacking the aryl group, were prepared. These guanidines contain a hydrophobic substituent on one nitroge