66892-33-9

Basic information

• Product Name: (3-METHOXY-PROPYL)-THIOUREA
• Synonyms: N-(3-METHOXYPROPYL)THIOUREA;(3-METHOXY-PROPYL)-THIOUREA;1-(3-METHOXYPROPYL)-2-THIOUREA
• CAS NO: 66892-33-9
• Molecular Formula: C₅H₁₂N₂OS
• Molecular Weight: 148.23
• Mol File: 66892-33-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-METHOXY-PROPYL)-THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: (3-METHOXY-PROPYL)-THIOUREA(66892-33-9)
• EPA Substance Registry System: (3-METHOXY-PROPYL)-THIOUREA(66892-33-9)

Safety Data

• Hazardous Substances Data: 66892-33-9(Hazardous Substances Data)

Usage

General Description

(3-Methoxy-propyl)-thiourea is a chemical compound with the molecular formula C6H14N2OS. It is an organosulfur derivative and a member of the thiourea family. (3-METHOXY-PROPYL)-THIOUREA is used in a variety of industrial applications, including as a corrosion inhibitor, a polymerization accelerator, and a chemical intermediate in the production of pharmaceuticals and pesticides. It is also used as a reagent in organic synthesis and as a component in the production of rubber and plastics. (3-Methoxy-propyl)-thiourea is known for its high solubility in water and its ability to interact with metal ions, making it useful in various industrial processes. It is important to handle this compound with care, as it can be harmful if ingested or inhaled, and can cause irritation to the skin and eyes.

Upstream product

• 17702-11-3 3-methoxypropyl isothiocyanate 

Downstream Products

• 850219-17-9 3-(3-methoxy-propyl)-5,5-diphenyl-2-thioxo-imidazolidin-4-one 

Relevant articles and documents

Substituted 5,5′-diphenyl-2-thioxoimidazolidin-4-one as CB 1 cannabinoid receptor ligands: Synthesis and pharmacological evaluation

A set of 30 substituted 5,5′-diphenyl-2-thioxoimidazolidin-4-one (thiohydantoins) derivatives was synthesized, and their affinity for the human CB1 cannabinoid receptor has been evaluated. These compounds are derived from the previously described cannabinoid ligands 5,5′- diphenylimidazolidine-2,4-dione (hydantoins). The replacement of the oxygen by a sulfur leads to an increase of the affinity while the function-i.e., inverse agonism-determined by [35S]-GTPγS experiments remains unaffected. Finally, to evaluate the molecular parameters that could influence the affinity of the thiohydantoins, molecular electrostatic potential as well as lipophilicity calculations were undertaken on representative thiohydantoins and hydantoins derivatives. In conclusion, 5,5′-bis-(4-iodophenyl)-3-butyl-2- thioxoimidazolidin-4-one (31) and 3-allyl-5,5′-bis(4-bromophenyl)-2- thioxoimidazolidin-4-one (32) possess the highest affinity for the CB 1 cannabinoid receptor described to date for the hydantoin and thiohydantoins series when compared in a same bioassay.