668971-16-2

Usage

Uses

Used in Pharmaceutical Industry:
5-(2-Methoxy-phenyl)-isoxazole-3-carboxylic acid is used as a building block for the development of pharmaceuticals due to its ability to form various heterocyclic compounds with potential therapeutic properties.
Used in Agrochemical Industry:
5-(2-Methoxy-phenyl)-isoxazole-3-carboxylic acid is used as a building block for the development of agrochemicals, contributing to the creation of new compounds with potential applications in agriculture.
Used in Medicinal Chemistry Research:
5-(2-Methoxy-phenyl)-isoxazole-3-carboxylic acid is used as a valuable tool in medicinal chemistry research for studying its potential therapeutic properties and exploring its biological activities.

InChI:InChI=1/C11H9NO4/c1-15-9-5-3-2-4-7(9)10-6-8(11(13)14)12-16-10/h2-6H,1H3,(H,13,14)

Upstream product

• 60943-39-7 ethyl 4-(2-methoxyphenyl)-2,4-dioxobutanoate 
• 579-74-8 2-Methoxyacetophenone 
• 110578-28-4 ethyl 5-(2-methoxyphenyl)isoxazole-3-carboxylate 
• 1427216-72-5 2-hydroxy-4-oxo-4-(2-methoxyphenyl)but-2-enoic acid ethyl ester 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 1450606-89-9 N-(1-adamantyl)-5-(2-methoxyphenyl)isoxazole-3-carboxamide 

Relevant academic research and scientific papers

Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment

Membrane-bound pyrophosphatases (mPPases) regulate energy homeostasis in pathogenic protozoan parasites and lack human homologues, which makes them promising targets in e.g. malaria. Yet only few nonphosphorus inhibitors have been reported so far. Here, w

ATF6 INHIBITORS AND USES THEREOF

Compounds as inhibitors of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis

Recent investigations showed that anandamide, the main endogenous ligand of CB1 and CB2 cannabinoid receptors, possesses analgesic, antidepressant and anti-inflammatory effects. In the perspective to treat inflammatory bowel disease (IBD), our approach was to develop new selective CB2 receptor agonists without psychotropic side effects associated to CB1 receptors. In this purpose, a new series of 3-carboxamido-5- aryl-isoxazoles, never described previously as CB2 receptor agonists, was designed, synthesized and evaluated for their biological activity. The pharmacological results have identified great selective CB2 agonists with in vivo anti-inflammatory activity in a DSS-induced acute colitis mouse model.

ANTIBACTERIAL BENZOIC ACID DERIVATIVES

The invention provides antimicrobial agents and methods of using the agents for sterilization, sanitation, antisepsis, disinfection, and treatment of infections in mammals.