668987-30-2

Upstream product

• 238425-68-8 (1R,5S,6R)-4-(tert-butyldimethylsiloxymethyl)-5-hydroxy-3-(prop-1-enyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one 
• 238424-94-7 (1R,5S,6R)-5-hydroxy-4-hydroxymethyl-3-[(E)-1-propenyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 668987-36-8 (1R,5S,6S)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-(tert-butyl-diphenyl-silanyloxy)-3-((E)-propenyl)-7-oxa-bicyclo[4.1.0]hept-3-en-2-one 

Relevant academic research and scientific papers

Synthesis of epoxyquinol A and related molecules: Probing chemical reactivity of epoxyquinol dimers and 2H-pyran precursors

Total syntheses of the epoxyquinoid dimers, epoxyquinols A, B, and epoxytwinol A (RKB-3564 D), have been accomplished employing [4 + 2] and [4 + 4] dimerization of 2H-pyran epoxyquinol monomers. Modifications of 2H-pyran precursors have been explored, inc

Synthesis of the Epoxyquinol Dimer RKB-3564 D: Utilization of an Alkoxysilanol to Promote [4 + 4] Dimerization

The synthesis of the epoxyquinol dimer RKB-3564 D (3) is reported, employing an alkoxysilanol protecting group to redirect the inherently favored [4 + 2] dimerization of 2H-pyran monomers to a [4 + 4] manifold. Preliminary mechanistic studies indicate tha