668990-46-3

Basic information

• Product Name: Ethanone,1-(2-ethyl-5-phenyl-3-furanyl)-(9CI)
• Synonyms: Ethanone,1-(2-ethyl-5-phenyl-3-furanyl)-(9CI)
• CAS NO: 668990-46-3
• Molecular Formula: C14H14O2
• Molecular Weight: 214.25976
• Product Categories: ETHYL
• Mol File: 668990-46-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone,1-(2-ethyl-5-phenyl-3-furanyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone,1-(2-ethyl-5-phenyl-3-furanyl)-(9CI)(668990-46-3)
• EPA Substance Registry System: Ethanone,1-(2-ethyl-5-phenyl-3-furanyl)-(9CI)(668990-46-3)

Safety Data

• Hazardous Substances Data: 668990-46-3(Hazardous Substances Data)

Upstream product

• 59624-45-2 3-acetyl-2-methoxy-5-phenylfuran 
• 925-90-6 ethylmagnesium bromide 

Relevant articles and documents

The first nucleophilic aromatic substitution of suitably activated 2-methoxyfurans with Grignard reagents

The reaction of 2-methoxyfuroates 1 with Grignard reagents 2 leads to tertiary alcohols or SNAr products depending on the position of the alkoxycarbonyl group. OMe-Displacement occurs only for 3-substituted derivatives. It takes place even for 3-acetyl-2-methoxyfuran while the presence of a further ester function at 4 position induces the formation of the sole 4-tertiary alcohol. The OMe-substitution has been verified for a wide range of furans and Grignard reagents and low yields have been found only in the reactions with the benzylic and allylic reagents which are delocalized anions. A mechanistic interpretation is given.