668995-06-0Relevant academic research and scientific papers
Total synthesis of (+)-xyloketal D, a secondary metabolite from the mangrove fungus Xylaria sp.
Krohn, Karsten,Riaz, Muhammad
, p. 293 - 294 (2007/10/03)
(+)-Xyloketal D was prepared in a one-pot multistep domino reaction by heating optically active 5-hydroxy-4-methyl-3-methylenepentan-2-one (R) in toluene with 2,4-dihydroxyacetophenone. The absolute configuration of the natural product was confirmed by preparation of the starting enone from a lactone of established absolute configuration.
Synthesis of xyloketals, natural products from the mangrove fungus Xylaria sp.
Krohn, Karsten,Riaz, Muhammad,Floerke, Ulrich
, p. 1261 - 1270 (2007/10/03)
The xyloketal family of compounds was synthesized by condensation of phloroglucinol (7) or 2,4-dihydroxyacetophenone (15) with the enone 8a or 14 in multistep, one-pot, domino reactions, leading to the xyloketals and 5-demethyl-xyloketals, respectively. I
