66900-71-8

Basic information

• Product Name: azanide, cyclohexanamine, platinum(+4) cation, trisulfate
• Synonyms: 1,2-Cyclohexanediamine, (1S-trans)-, platinum sulfate complex;Nsc289543;Platinum, (1,2-cyclohexanediamine-N,N')sulfato(2-)-o,o']-, (sp-4-2) (1S-trans)]-
• CAS NO: 66900-71-8
• Molecular Formula: C12H30N4O12Pt2S3
• Molecular Weight: 908.7492
• Mol File: 66900-71-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 134.5°Cat760mmHg
• Flash Point: 32.2°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.46mmHg at 25°C
• CAS DataBase Reference: azanide, cyclohexanamine, platinum(+4) cation, trisulfate(CAS DataBase Reference)
• NIST Chemistry Reference: azanide, cyclohexanamine, platinum(+4) cation, trisulfate(66900-71-8)
• EPA Substance Registry System: azanide, cyclohexanamine, platinum(+4) cation, trisulfate(66900-71-8)

Safety Data

• Hazardous Substances Data: 66900-71-8(Hazardous Substances Data)

Usage

Uses

(SP-4-2)-[(1S,2S)-1,2-Cyclohexanediamine-κN1,κN2][sulfato(2-)-κO,κO'']platinum is a useful compound for preparing anti-tumor agents that specifically targets (GLUT)-mediated transport.

InChI:InChI=1/C6H12N2.H2O4S.Pt/c7-5-3-1-2-4-6(5)8;1-5(2,3)4;/h5-8H,1-4H2;(H2,1,2,3,4);/q-2;;+2

Upstream product

• 61848-66-6 cis-dichloro-(cis-1,2-diaminocyclohexane)platinum(II) 
• 66845-32-7 trans-cyclohexamethylene diaminediiodoplatinum(II) 
• 38780-40-4 {(1R,2R)-cyclohexane-1,2-diamine}dichloridoplatinum(II) 

Downstream Products

• 99144-84-0 ((C₆H₁₁)CH₂COO)2Pt(NH₂(C₆H₁₀)NH₂) 
• 96322-13-3 bis(cyclohexanecarboxylato)(1,2-diaminocyclohexane)platinum(II) 
• 96322-20-2 ((CH₂)4CHCCOO)2Pt(NH₂(C₆H₁₀)NH₂) 

Relevant articles and documents

Metal-polysaccharide conjugates: compositions, synthesis and methods for cancer therapy

The current disclosure, in one embodiment, includes a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid. According to another embodiment, the disclosure provides a method of synthesizing a polysaccharide conjugate by covalently bonding a monomeric amino acid having an O-group to a polysaccharide and by conjugating a metal to the O-group to form a polysaccharide conjugate. According to a third embodiment, the disclosure relates to a method of killing a cancer cell by administering to the cell an effective amount of a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid.