669004-75-5Relevant academic research and scientific papers
New chemotypes for cathepsin K inhibitors
Teno, Naoki,Irie, Osamu,Miyake, Takahiro,Gohda, Keigo,Horiuchi, Miyuki,Tada, Sachiyo,Nonomura, Kazuhiko,Kometani, Motohiko,Iwasaki, Genji,Betschart, Claudia
, p. 2599 - 2603 (2008/12/21)
Cyano pyrimidine acetylene and cyano pyrimidine t-amine, which belong to a new chemical class, were prepared and tested for inhibitory activities against cathepsin K and the highly homologous cathepsins L and S. The use of novel chemotypes in the developm
HETEREOARYL NITRILE DERIVATIVES
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Page 76-77, (2008/06/13)
The invention provides compounds of Formula (I) or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical con
