669064-04-4Relevant articles and documents
Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5negative allosteric modulation
Gómez-Santacana, Xavier,Dalton, James A.R.,Rovira, Xavier,Pin, Jean Philippe,Goudet, Cyril,Gorostiza, Pau,Giraldo, Jesús,Llebaria, Amadeu
, p. 567 - 576 (2017/01/28)
Modulation of metabotropic glutamate receptor 5 (mGlu5) with partial allosteric antagonists has received increased interest due to their favourable in?vivo activity profiles compared to the unfavourable side-effects of full inverse agonists. He
Pd complexes with trans-chelating ligands composed of two pyridyl groups and rigid π-conjugated backbone
Jung, Miso,Suzaki, Yuji,Saito, Takashi,Shimada, Kyoichi,Osakada, Kohtaro
experimental part, p. 168 - 174 (2012/08/28)
1,2-Bis(2-pyridylethynyl)benzene derivatives, having two pyridyl groups and π-conjugated backbone, were prepared from the 1:2 Sonogashira reaction of 1,2-diiodobenzene with 2-alkynyl pyridines. The obtained ligands react with the palladium(II) complexes such as [PdCl2(cod)] and [PdCl 2(MeCN)2] to form the complexes with the ligands coordinated in a trans-chelating bidentate mode. The ligand obtained from 1,3-diiodobenzene and 2-alkynyl pyridine bridges two Pd(II) centers, yielding a dipalladium complex. A dichloropalladium complex with the trans-chelating ligand, containing two methoxy groups in the central arylene group, promotes coupling of phenyl lithium and of phenyl acetylene to yield the respective homo-coupling products. The ligand displacement reactions of {bis(2-pyridylethynyl)benzene}palladium(II) complex with phosphine and dinitrogen ligands, such as PPh3, dppe, dppb, en, tmeda, bpy and phen, takes place smoothly to release the trans-chelating ligand.
Banana-shaped oligo(aryleneethynylene)s: Synthesis and light-emitting characteristics
Yamaguchi, Yoshihiro,Kobayashi, Shigeya,Wakamiya, Tateaki,Matsubara, Yoshio,Yoshida, Zen-Ichi
, p. 7040 - 7044 (2007/10/03)
(Chemical Equation Presented) Pick of the bunch: Banana-shaped molecules 1 and 2 containing dimethoxybenzene and pyridine units are highly efficient emitters of violet light despite the interruption of the π conjugation because of meta substitution. The c
