669076-56-6Relevant academic research and scientific papers
Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins
De Corte, Bart L.,Kinney, William A.,Liu, Li,Ghosh, Shyamali,Brunner, Livia,Hoekstra, William J.,Santulli, Rosemary J.,Tuman, Robert W.,Baker, Judith,Burns, Candace,Proost, Jef C.,Tounge, Brett A.,Damiano, Bruce P.,Maryanoff, Bruce E.,Johnson, Dana L.,Galemmo Jr., Robert A.
, p. 5227 - 5232 (2004)
The synthesis and SAR of a new class of piperidine-based αvβ3/αvβ5 integrin antagonists is described.
PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS
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Page 133, (2010/11/30)
The invention is directed to piperidinyl compounds of formula (I) and (II) that selectively bind integrin receptors and methods for treating an integrin mediated disorder, wherein W, R2, Z and q are described in the application.
