66910-37-0Relevant academic research and scientific papers
5-FLUOROURACIL COMPOUNDS
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Paragraph 0146; 0147, (2019/08/08)
Provided herein are 5-fluorouracil derived acetal and hemiaminal ether compounds, their preparation and their uses, such as treating liver diseases or various types of cancer.
SULFONAMIDE DERIVATIVES
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, (2008/06/13)
The object is to provide a compound having matrixmetalloproteinase-13 inhibitory activity and aglycanase inhibitory activity. A compound of the following formula (I) or a pharmacologically acceptable salt, ester or other derivative thereof:{R1: H, NHOH; R2: H, optionally substituted alkyl, cycloalkyl, a group -AR6 [A: an alkylene which may be optionally interrupted by O, -S(O)m- or -N(R9); R6: a group (II), (III), (IV)X: O, S, -N(R10)-, -C(R11)(R12)-; Y: O, CO, -S(O)n-, -N(R10)-, -C(R11)(R12)-; R7, R8: H, alkyl, COOH, optionally subsituted alkyl, etc.; R9, R10, R11,R12: H, alkyl, etc.; m, n: 0 to 2]R3: H, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted alkenyl, optionally substituted alkynyl; R4: optionally substituted (hetero)arylene; R5: optionally substituted alkyl, optionally substituted (hetero)aryl}.
