66918-21-6

Basic information

• Product Name: 2,5-Bis(aminomethyl)tetrahydrofuran
• Synonyms: 2,5-Bis(aminomethyl)tetrahydrofuran;1,6-Diamino-2,5-anhydro-1,3,4,6-tetradeoxyhexitol;Tetrahydro-2,5-furanebis(methylamine)
• CAS NO: 66918-21-6
• Molecular Formula: C6H14N2O
• Molecular Weight: 130.19
• Product Categories: Heterocycles
• Mol File: 66918-21-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 227.798°C at 760 mmHg
• Flash Point: 100.922°C
• Appearance: /
• Density: 1.007g/cm³
• Vapor Pressure: 0.076mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 2,5-Bis(aminomethyl)tetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Bis(aminomethyl)tetrahydrofuran(66918-21-6)
• EPA Substance Registry System: 2,5-Bis(aminomethyl)tetrahydrofuran(66918-21-6)

Safety Data

• Hazardous Substances Data: 66918-21-6(Hazardous Substances Data)

Usage

Chemical Properties

Dark Yellow Oil

InChI:InChI=1/C6H14N2O/c7-3-5-1-2-6(4-8)9-5/h5-6H,1-4,7-8H2

Upstream product

• 99261-34-4 cis-2,5-Bis-phthalimidomethyl-tetrahydro-furan 
• 1268257-14-2 5-(azidomethyl)furan-2-carbaldehyde 
• 1623-88-7 5-chloromethylfurfural 
• 1883-75-6 2,5-bis-(hydroxymethyl)furan 
• 2213-51-6 (furan-2,5-diyl) dimethanamine 
• 823-82-5 2,5-diformylfurane 
• 67-47-0 5-hydroxymethyl-2-furfuraldehyde 
• 99261-31-1 (2S,5S)-Tetrahydro-furan-2,5-dicarboxylic acid diamide 
• 99261-34-4 C₂₂H₁₈N₂O₅ 
• 81370-96-9 (-)-(2S,5S)-trans-tetrahydrofuran-2,5-dicarboxylic acid 
• 99340-08-6 (2S,5S)-tetrahydrofuran-2,5-dicarbonyl dichloride 

Downstream Products

• 99261-33-3 C₂₀H₂₆N₂O₅S₂ 

Relevant articles and documents

Method for preparing 1, 6-hexamethylenediamine from 5-hydroxymethylfurfural

The invention relates to a method for preparing 1, 6-hexamethylenediamine from 5-hydroxymethylfurfural, which is characterized in that the 5-hydroxymethylfurfural is used as a raw material, and the 1, 6-hexamethylenediamine is synthesized by a two-step method under the action of a catalyst. The method comprises the following steps: 1) in a hydrogen atmosphere, reacting the raw material 5-hydroxymethylfurfural with ammonia in the presence of a reductive amination catalyst to generate 2, 5-dimethylamine tetrahydrofuran; and 2) continuing the reaction, and carrying out a ring-opening reaction on the hydrodeoxygenation catalyst to produce the target product 1, 6-hexamethylenediamine. The method is characterized in that the reductive amination catalyst in the step 1) is an M1-M2 supported multi-metal component catalyst. The method is characterized in that the hydrodeoxygenation catalyst in the step 2) is a supported catalyst, and the metal active component is selected from one or more of transition metal elements Rh, Re, Pt, Ir, Pd and Ru. The 1, 6-hexamethylenediamine is produced by using the bio-based material monomer 5-hydroxymethylfurfural as the raw material, so that the method is green and clean, the process is easy to operate, the yield is high, and a wide application prospect is provided for biomass conversion.

METHOD FOR PRODUCING 2,5-BIS(AMINOMETHYL)TETRAHYDROFURAN

To provide a method that can efficiently produce 2,5-bis(aminomethyl)tetrahydrofuran. The method for producing 2,5-bis(aminomethyl)tetrahydrofuran, the method including subjecting 2,5-bis(aminomethyl)furan to a reaction with hydrogen source by using a hydrogenation catalyst to obtain 2,5-bis(aminomethyl)tetrahydrofuran.

2,5-BIS(AMINOMETHYL)FURAN DIHYDROHALIDE AND PRODUCTION METHOD OF THE SAME, AND PRODUCTION METHOD OF 2,5-BIS(AMINOMETHYL)FURAN

PROBLEM TO BE SOLVED: To provide a method for stably supplying 2,5-bis(aminomethyl)furan. SOLUTION: In synthesizing 2,5-bis(aminomethyl)furan by the hydrogenation reaction of fran-2,5,-dioxime, by preliminarily adding two equivalents or more of a hydrohalic acid, the hydrohalic acid reacts simultaneously with hydrogenation so that 2,5-bis(aminomethyl)furan dihydrohalide is obtained with high selectivity, and further the diamine can be easily supplied by adding a base to the dihydrohalide. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT