66920-03-4

Upstream product

• 1711-09-7 3-bromobenzoyl chloride 
• 75-08-1 ethanethiol 
• 585-76-2 m-bromobenzoic acid 

Downstream Products

• 630050-32-7 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 160911-82-0 1-Bromo-3-(ethylsulfanyl-difluoro-methyl)-benzene 
• 160911-74-0 1-Bromo-3-(chloro-difluoro-methyl)-benzene 
• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 585-76-2 m-bromobenzoic acid 
• 75-08-1 ethanethiol 
• 160911-77-3 3-Bromo-dithiobenzoic acid ethyl ester 

Relevant academic research and scientific papers

From carboxylic acids to the trifluoromethyl group using BrF3

Organic trifluoromethyl derivatives were made from aromatic and aliphatic carboxylic acids by transforming them first into the corresponding dithioesters followed by reaction with bromine trifluoride under mild conditions (0 °C, 2 min).

Highly efficient iron(II) chloride/N-bromosuccinimide-mediated synthesis of imides and acylsulfonamides

We have developed a general and highly efficient iron(II) chloride/N-bromosuccinimide (NBS)-mediated method for the synthesis of imides and acylsulfonamides via couplings of thioesters with carboxamides/sulfonamides, and the method is simple, economical and shows practical advantages.

A Novel Method for Converting Aromatic Acids into Trifluoromethyl Derivatives using BrF3

Aryltrifluoromethyl derivatives are obtained in good yields from the corresponding aryl carboxylic acids by reacting their dithionic esters with BrF3 under very mild conditions.