66941-04-6 Usage
Origin
Derived from the fungus Tolypocladium inflatum
Classification
Natural cyclic polypeptide
Primary Use
Immunosuppressant in organ transplant patients
Mechanism of Action
Inhibits the activity of T-lymphocytes
Additional Potential Uses
Treatment of autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), certain types of cancer
Additional Properties
Anti-inflammatory and anti-fibrotic effects
Side Effects
Kidney damage, hypertension, increased risk of infections
Precaution
Must be used under the supervision of a healthcare professional
Check Digit Verification of cas no
The CAS Registry Mumber 66941-04-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,9,4 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 66941-04:
(7*6)+(6*6)+(5*9)+(4*4)+(3*1)+(2*0)+(1*4)=146
146 % 10 = 6
So 66941-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H18N2O3/c1-7(2)5-6-8-9(14)12(3)11(16)13(4)10(8)15/h7-8H,5-6H2,1-4H3
66941-04-6Relevant articles and documents
Selective reduction of barbituric acids using SmI2/H 2O: Synthesis, reactivity, and structural analysis of tetrahedral adducts
Szostak, Michal,Sautier, Brice,Spain, Malcolm,Behlendorf, Maike,Procter, David J.
, p. 12559 - 12563 (2013/12/04)
Making a mark: Since the 1864 landmark discovery by Adolf von Baeyer, barbituric acids have played a prominent role in organic synthesis. Herein, the first chemoselective monoreduction of barbituric acids to the corresponding hemiaminals is described. The method delivers mono- and bicyclic hemiaminal products by a general single-electron-transfer polarity reversal mechanism. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://angewandte.org/open.
