66952-47-4Relevant academic research and scientific papers
Easy and General Method for the Preparation of m- and p-Acylbenzoic Acids: A New Synthesis of rac-Suprofen
Camps, Pelayo,Gimenez, Silvia,Farres, Xavier,Mauleon, David,Carganico, Germano
, p. 641 - 644 (2007/10/02)
A method for the preparation of m- and p-acylbenzoic acids 3 based on the Claisen condensation of isophthalic or terephthalic diesters 1 with α-methylenecarboxylic esters 2 is described. p-Propionylbenzoic acid p-4 (R=Me) is used in a new synthesis of rac-suprofen (11). Key Words: Acylbenzoic acids / Claisen condensation / rac-Suprofen / Thalium(III) nitrate
Intermediates for preparing optically active carboxylic acids
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, (2008/06/13)
A process is described for preparing optically active alpha-arylalkanoic acids consisting of rearranging an optically active ketal of formula STR1 in which the substituents have the meaning given in the description of the invention.
