66969-81-1Relevant academic research and scientific papers
Levulinic acid salt
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, (2008/06/13)
The invention concerns a levulinic acid addition salt of the antihypertensive agent 4-amino-6,7-dimethoxy-2-[4-(5-methylthio-1,3,4-oxadiazole-2-carbonyl]piperazin-1-yl)quinazoline in which the base to acid mole ratio is 1 to from 1.25-1.35. The salt is characterized in having improved water solubility and stability compared to the levulinate salt having a 1:1 ratio of base to acid.
1,3,4-Oxadiazole amides
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, (2008/06/13)
The 4-amino-6,7-dimethoxy-2-[4-(5-lower alkylthio-1,3,4-oxadiazole-2-carbonyl)-piperazin-1-yl]-quinazolines are potent antihypertensive drugs which have little or no α-adrenergic blocking activity.
