669706-08-5Relevant academic research and scientific papers
Synthesis of a malaria candidate glycosylphosphatidylinositol (GPI) structure: A strategy for fully inositol acylated and phosphorylated GPIs
Lu, Jun,Jayaprakash,Schlueter, Urs,Fraser-Reid, Bert
, p. 7540 - 7547 (2007/10/03)
A congener of the glycosylphosphatidylinositol (GPI) membrane anchor present on the cell surface of the malaria pathogen Plasmodium falciparum has been synthesized. This GPI is an example of a small number of such membrane anchors that carry a fatty acyl
First synthesis of a malarial prototype: A fully lipidated and phosphorylated GPI membrane anchor
Lu, Jun,Jayaprakash,Fraser-Reid, Bert
, p. 879 - 882 (2007/10/03)
A strategy is described for syntheses of a fully lipidated and phosphorylated prototype of the GPI of Plasmodium falciparum, the causative agent of lethal cerebral, drug-resistant malaria. Orthoesters, prepared in four steps from D-mannose, and methyl α-D
