66976-53-2 Usage
Potential therapeutic benefits
modulation of excitatory neurotransmitters in the brain
Investigated for
anti-inflammatory and analgesic properties
Potential applications
treatment of chronic pain and neurodegenerative diseases
Used as
building block in the synthesis of pharmaceutical and biologically active compounds
Check Digit Verification of cas no
The CAS Registry Mumber 66976-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,9,7 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 66976-53:
(7*6)+(6*6)+(5*9)+(4*7)+(3*6)+(2*5)+(1*3)=182
182 % 10 = 2
So 66976-53-2 is a valid CAS Registry Number.
66976-53-2Relevant academic research and scientific papers
Palladium-catalyzed coupling reaction of amino acids (esters) with aryl bromides and chlorides
Ma, Fangfang,Xie, Xiaomin,Ding, Lina,Gao, Jinsheng,Zhang, Zhaoguo
experimental part, p. 9405 - 9410 (2011/12/14)
The bulky and electron-rich MOP type ligands and Pd(dba)2 combinations showed high efficiency for the coupling reactions of amino acids and inactive aryl halides to give N-aryl amino acids. Under the catalytic conditions, not only α-amino acids, but also β-, γ-, and δ-amino acids have been coupled with aryl chlorides in moderate to high yields; in the case of optically pure β-amino acids as substrates, the optical purities of the coupling products retained.
