66977-04-6Relevant articles and documents
PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER
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Paragraph 00339; 00340, (2017/05/02)
This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the use of t
Novel cyclopropyl β-amino acid analogues of pregabalin and gabapentin that target the α2-δ protein
Schwarz, Jacob B.,Gibbons, Sian E.,Graham, Shelley R.,Colbry, Norman L.,Guzzo, Peter R.,Le, Van-Duc,Vartanian, Mark G.,Kinsora, Jack J.,Lotarski, Susan M.,Li, Zheng,Dickerson, Melvin R.,Su, Ti-Zhi,Weber, Mark L.,El-Kattan, Ayman,Thorpe, Andrew J.,Donevan, Sean D.,Taylor, Charles P.,Wustrow, David J.
, p. 3026 - 3035 (2007/10/03)
As part of a program aimed at generating compounds with affinity for the α2-δ subunit of voltage-gated calcium channels, several novel β-amino acids were prepared using an efficient nitroalkane-mediated cyclopropanation as a key step. Depending
TETRAZOLE AND OXADIAZOLONE SUBSTITUTED β-AMINO ACID DERIVATIVES
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Page 55-56, (2010/02/08)
This invention relates to novel tetrazole and oxadiazalone β-amino acids derivatives of the formula (I, II), wherein G is (III, IV) wherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing the
