669776-71-0

Basic information

• Product Name: Cytidine, 5-[4-(benzoylthio)-1-butynyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2' -deoxy-
• CAS NO: 669776-71-0
• Molecular Formula: C41H39N3O7S
• Molecular Weight: 717.843
• Mol File: 669776-71-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cytidine, 5-[4-(benzoylthio)-1-butynyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2' -deoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Cytidine, 5-[4-(benzoylthio)-1-butynyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2' -deoxy-(669776-71-0)
• EPA Substance Registry System: Cytidine, 5-[4-(benzoylthio)-1-butynyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2' -deoxy-(669776-71-0)

Safety Data

• Hazardous Substances Data: 669776-71-0(Hazardous Substances Data)

Upstream product

• 211510-45-1 but-1-yn-4-yl thiobenzoate 
• 98-91-9 thiobenzoic acid 
• 611-53-0 5-Iodo-2'-deoxycytidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 845620-48-6 1-[2-deoxy-5-O-(4,4′-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-5-iodocytosine 
• 647852-34-4 5-(4-benzoylthio-1-butynyl)-2'-deoxycytidine 

Downstream Products

• 647852-37-7 4-[5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidin-5-yl]but-3-ynyl tert-butyl disulfide 
• 669776-75-4 4-[3'-O-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidin-5-yl]but-3-ynyl tert-butyl disulfide 
• 669776-73-2 4-[3'-O,4-N-diacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidin-5-yl]but-3-ynyl tert-butyl disulfide 

Relevant articles and documents

2'-deoxycytidines carrying amino and thiol functionality: synthesis and incorporation by Vent (exo-) polymerase.

[reaction: see text] The synthesis of 2'-deoxycytidine nucleosides bearing amino and thiol groups appended to the 5-position of the nucleobase via a butynyl linker is described. The corresponding triphosphates were then synthesized from the nucleoside and incorporated into oligonucleotides by Vent (exo(-)) DNA polymerase. The ability of Vent (exo(-)) polymerase to amplify oligonucleotides containing these functionalized cytidine derivatives in a polymerase chain reaction (PCR) was demonstrated for the amino-functionalized derivative.