67019-91-4

Usage

Uses

Used in Organic Synthesis:
Dibenzofuran, 3,7-dibromois utilized as a key intermediate in organic synthesis, serving as a building block for the production of more complex chemical compounds. Its unique structure allows for the creation of a wide range of derivatives, expanding the scope of chemical reactions and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Dibenzofuran, 3,7-dibromois employed as a starting material for the synthesis of various pharmaceutical agents. Its unique chemical properties enable the development of new drugs with potential therapeutic benefits, contributing to the advancement of medicine and healthcare.
Used in Agrochemical Industry:
Dibenzofuran, 3,7-dibromoalso finds application in the agrochemical industry, where it is used as a precursor for the synthesis of agrochemicals such as pesticides and herbicides. Its unique structure and properties allow for the development of more effective and targeted agrochemicals, enhancing crop protection and agricultural productivity.

Upstream product

• 26608-06-0 3-bromodibenzofuran 
• 232940-84-0 2-methoxy-2’-amino-4,4’-dibromobiphenyl 
• 91371-12-9 4,4'-dibromo-2,2'-dinitrobiphenyl 
• 232940-83-9 2-methoxy-2’-nitro-4,4’-dibromobiphenyl 
• 132-64-9 dibenzofuran 
• 3460-18-2 1,4-dibromo-2-nitrobenzene 

Downstream Products

• 33763-36-9 3,7-dicyano-dibenzofuran 
• 1093403-30-5 7-bromo-N,N-diphenyldibenzo[b,d]furan-3-amine 

Relevant academic research and scientific papers

Double-(S, S - dioxo - dibenzo thiophene) and high output compound and its preparation method and application

The invention discloses a bi(S,S-dioxo-dibenzothiophene) five-membered ring compound and a preparation method and application thereof. The existence of bi-sulfuryl in the bi(S,S-dioxo-dibenzothiophene) five-membered ring compound is more beneficial for improving the electron affinity of molecules. Alkyl chains are introduced on a five-membered ring, so that the solubility of monomers in an organic solvent can be obviously improved. The plane conjugacy of the compound is better, and is beneficial for the transmission of a current carrier. Higher D-A mutual effect existing in the molecules of the compound endows higher fluorescence of the material. The bi(S,S-dioxo-dibenzothiophene) five-membered ring compound is synthesized and obtained through common organic chemistry reactions such as substitution reactions, Suzuki coupling and ring-closure reactions and oxidation reactions. The compound has good solubility in the organic solvent, and is suitable for solution processing. The compound has wide application prospects in the fields of organic luminescence display, organic photovoltaic cells and organic field-effect tubes.

Photophysical properties and optical power limiting ability of Pt(II) polyynes bearing fluorene-type ligands with ethynyl units at different positions

Two series of Pt(II) polyynes bearing fluorene-type ligands with ethynyl units at different positions have been synthesized. In the absorption spectra, the Pt(II) polyynes bearing fluorene-type ligands with ethynyl units at 3,6-position have blue-shift with respect to the corresponding analogs bearing fluorene-type ligands with ethynyl units at 2,7-position, showing better transparency in the visible light region. Moreover, the Pt(II) polyynes bearing fluorene-type ligands with ethynyl units at 3,6-position show stronger triplet emission than corresponding analogs bearing fluorene-type ligands with ethynyl units at 2,7-position in the photoluminescent (PL) spectra. Furthermore, these Pt(II) polyynes were applied to optical power limiting (OPL) field. The Pt(II) polyynes bearing fluorene-type ligands with ethynyl units at 2,7-position show better OPL performance than the corresponding analogs with fluorene-type ligands of ethynyl units at 3,6-position. Therefore, changing the position of the ethynyl units in fluorene-type ligands can not only effectively control the photophysical properties of the Pt(II) polyynes, but also has an important effect on their OPL ability.

Facile preparation of dibenzoheterocycle-functional nanoporous polymeric networks with high gas uptake capacities7

A consolidated ionothermal strategy was developed for the polymerization of thermally unstable nitriles to construct high performance materials with permanent porosity, and carbazole, dibenzofuran, and dibenzothiophene were separately introduced into covalent triazine-based networks to investigate the effects of heterocycles on the gas adsorption performance. Three nitriles, namely 3,6-dicyanocarbazole, 3,6-dicyanodibenzofuran, and 3,6- dicyanodibenzothiophene, were designed and synthesized, which were readily converted to heat-resistant intermediates at a moderate temperature and then polymerized to create highly porous poly(triazine) networks instead of the traditional one-step procedure. This documents an improved strategy for the successful construction of heterocyclic-functional triazine-based materials. The chemical structures of monomers and polymers were confirmed by 1H NMR, FTIR, and elemental analysis. Such polymers with high physical-chemical stability and comparable BET surface areas can uptake 1.44 wt % H2 at 77 K/1 bar and 14.0 wt % CO2 at 273 K/1 bar and present a high selectivity for gas adsorption of CO2 (CO2/N2 ideal selectivity up to 45 at 273K/1.0 bar). The nitrogen- and oxygen-rich characteristics of carbazole and dibenzofuran feature the networks strong affinity for CO2 and thereby high CO2 adsorption capacity. This also helps to thoroughly understand the influence of pore structure and chemical composition on the adsorption properties of small gas molecules.

Dicationic dibenzofuran and dibenzothiophene compounds and methods of use thereof

Methods of treating Pneumocystis carinii pneumonia comprise administering a therapeutically effective amount of a dicationic dibenzofuran compound described by Formula (I). Methods of treating Pneumocystis carinii pneumonia also comprise administering a therapeutically effective amount of a dicationic dibenzothiophene compound described by Formula (II). Novel compounds are also disclosed, and are represented by the Formulae (I) and (II).

Dicationic dibenzofuran derivatives as anti-Pneumocystis carinii pneumonia agents: Synthesis, DNA binding affinity, and anti-P. carinii activity in an immunosuppressed rat model

Previous work from our laboratory shows that compounds with two cations linked by a carbazole spacer were highly potent anti-P. carinii agents. A prodrug approach designed to increase oral activity of the dicationic carbazoles by converting amidine groups to amidoxime groups was unsuccessful. The ring nitrogen was implicated as playing a role in the lack of activity of carbazole amidoximes. The current study was designed to determine if replacement of the carbazole ring nitrogen by isosteric oxygen to form dibenzofurans would improve effectiveness of amidoxime prodrugs. Eight dibenzofuran dicationic derivatives were synthesized and evaluated for anti- P. carinii activity in an immunosuppressed rat model. Since DNA binding has been hypothesized to play a key role in antimicrobial activity of dicationic compounds, the compounds were examined for their binding affinity to calf thymus DNA and a poly-dA·poly-dT oligomer. While several of the compounds were more potent anti-P. carinii agents than pentamidine, the corresponding amidoximes were significantly less effective than the amidoxime of pentamidine. No direct quantitative correlation was determined between DNA binding affinity and anti-P. carinii activity, but all active compounds were strong DNA binding agents.