670225-05-5Relevant academic research and scientific papers
Synthesis of Pyridazine Derivatives through the Unexpected Intermediate 5-Amino-4-Cyano-2,3-Dihydro-Furan-2,3-Disulfonic Acid Disodium Salt
Cacciari, Barbara,Spalluto, Giampiero,Ferretti, Valeria
, p. 1065 - 1069 (2003)
An unexpected compound (5-amino-4-cyano-2,3-dihydrofuran-2,3-disulfonic acid disodium salt, 4) was isolated from the reaction of glyoxale bis hydrogen sulfite disodium salt with malononitrile. Its structure was undoubtly identified through crystal structure analysis. Compound 4 was highly stable and it was isolated easily and in a very high yield. Its reactivity was studied in the reactions with some hydrazine derivatives in order to obtain different pyridazine analogs.
