670259-35-5Relevant academic research and scientific papers
Transannulation of Pyridotriazoles with Naphthoquinones and Indoles: Synthesis of Benzo[f]Pyrido[1,2-a]Indoles and Indolizino[3,2-b]indoles
Rawat, Deepa,Adimurthy, Subbarayappa
, p. 71 - 76 (2021/10/29)
Ruthenium catalysed denitrogenative transannulation of pyridotriazoles with naphthoquinones provided the transannulated benzo[f]pyrido[1,2-a]indoles derivatives in good to excellent yields. While pyridotriazoles with indoles in presence of PivOH and oxone yield indolizino[3,2-b]indoles under metal-free conditions. Quinone annulation proceeds through ruthenium-carbenoid intermediate while indole annulation may proceed via a diazo-pyridinium intermediate. Control experiments suggest that both the transformations follow the ionic mechanism. (Figure presented.).
Copper(II)-catalyzed carbon-carbon triple bond cleavage of internal alkynes for the synthesis of annulated indolizines
Sun, Jinwei,Wang, Fuyao,Hu, Huayou,Wang, Xiangshan,Wu, Hui,Liu, Yun
, p. 3992 - 3998 (2014/05/20)
Cleavage of C≡C bond in butynedioates via copper(II)-catalyzed reaction has been achieved, leading to the synthesis of benzo[f]pyrido[1,2-a] indole-6,11-diones in high yields by one-pot three-component reactions. In this unprecedented C≡C bond cleavage reaction of internal alkynes, both fragments from the alkyne are successively incorporated into the products.
