67027-80-9

Basic information

• Product Name: 1,2-CYCLOHEXANEDIOL, 4-(1,1-DIMETHYLETHYL)-
• Synonyms: 1,2-CYCLOHEXANEDIOL, 4-(1,1-DIMETHYLETHYL)-;4-TERT-BUTYL- (7CI);4-TERT-BUTYL-1,2-CYCLOHEXANEDIOL;4-TERT-BUTYLCYCLOHEXANE-1,2-DIOL
• CAS NO: 67027-80-9
• Molecular Formula: C₁₀H₂₀O₂
• Molecular Weight: 172.2646
• Mol File: 67027-80-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 263.7±8.0 °C(Predicted)
• Appearance: /
• Density: 1.033±0.06 g/cm3(Predicted)
• PKA: 14.81±0.60(Predicted)
• CAS DataBase Reference: 1,2-CYCLOHEXANEDIOL, 4-(1,1-DIMETHYLETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-CYCLOHEXANEDIOL, 4-(1,1-DIMETHYLETHYL)-(67027-80-9)
• EPA Substance Registry System: 1,2-CYCLOHEXANEDIOL, 4-(1,1-DIMETHYLETHYL)-(67027-80-9)

Safety Data

• Hazardous Substances Data: 67027-80-9(Hazardous Substances Data)

Usage

General Description

1,2-Cyclohexanediol, 4-(1,1-dimethylethyl)- is a chemical compound that belongs to the class of diols, which are organic compounds containing two hydroxyl groups. This specific compound has a cyclohexane ring structure and a tert-butyl group attached to the fourth carbon of the ring. It is commonly used as a solvent, a fragrance ingredient, and as a precursor in the synthesis of other organic compounds. It has a variety of industrial applications, including use in the production of pharmaceuticals, cosmetics, and personal care products. Additionally, it is also used as an intermediate in the manufacturing of resins, flavors, and fragrances.

Upstream product

• 2228-98-0 4-tert-butylcylohexene 
• 35376-39-7 cis 4-tert-butylcyclohexen-1-ol 
• 17502-34-0 cis-5-tert-butylcyclohex-2-en-1-ol 
• 98-29-3 4-tert-Butylcatechol 

Downstream Products

• 98-54-4 para-tert-butylphenol 
• 98-29-3 4-tert-Butylcatechol 

Relevant articles and documents

Catalytic hydrogenation of aromatic rings catalyzed by Pd/NiO

A simple and efficient heterogeneous palladium catalyst was prepared for aromatic ring hydrogenation. The catalyst was prepared by a reduction-deposition method and exhibited high activity and selectivity for the hydrogenation of a variety of substituted aromatic compounds to the corresponding cyclohexane and cyclohexanol derivatives with up to 99% yields. The catalyst was characterized by BET, TEM, XRD, XPS and ICP. Meanwhile the reusability of the catalyst was investigated, and it can be reused for several runs without significant deactivation.

Efficient oxidation of 1,2-diols into a-hydroxyketones catalyzed by organotin compounds

Electrochemical oxidation of 1,2-diols with a catalytic amount of an organotin compound and a bromide ion as mediators has been developed. Various cyclic and acyclic 1,2-diols were oxidized into the corresponding α-hydroxyketones in good to excellent yields without C-C bond cleavage. Also, oxidation with the use of chemical oxidants was accomplished in the presence of a catalytic amount of an organotin compound. These reactions could discriminate 1,2-diols from isolated hydoxyl groups or 1,3-diols. In the case of a conformationally restricted cyclic 1,2-diol, the axial hydroxyl group was oxidized exclusively. Mono-, di-, and trialkylated tin compounds were examined as mediators and dialkylated tin compounds showed higher catalytic activity than mono- and trisubstituted ones. Me2SnCl2 was found to be the most suitable mediator for the selective oxidation..

Highly trans-selective intramolecular pinacol coupling of dials catalyzed by bulky Cp2TiPh

Cp2Ti(Ph)Cl in the presence of Me3SiCl and Zn provides an effective pinacol coupling catalyst for aromatic and aliphatic aldehydes.