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3-(aminomethyl)benzenesulfonamide hydrochloride is a chemical compound characterized by a sulfonamide functional group attached to a benzene ring, featuring an amino-methyl substituent. It is recognized for its pharmaceutical applications, particularly as an antibiotic, diuretic, and antihypertensive agent. The hydrochloride salt form enhances its water solubility, facilitating oral or intravenous administration. Its mechanism of action involves the inhibition of dihydrofolic acid synthesis, which is essential for the production of purines and pyrimidines, thereby disrupting bacterial growth and contributing to their demise. 3-(aminomethyl)benzenesulfonamide hydrochloride has demonstrated efficacy in treating a range of bacterial infections and is considered a widely used and well-tolerated medication.

670280-13-4

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670280-13-4 Usage

Uses

Used in Pharmaceutical Industry:
3-(aminomethyl)benzenesulfonamide hydrochloride is used as an antibiotic for its ability to inhibit bacterial growth by disrupting the synthesis of dihydrofolic acid, a crucial component for the production of purines and pyrimidines necessary for bacterial replication.
Used in Diuretic Applications:
In the pharmaceutical industry, 3-(aminomethyl)benzenesulfonamide hydrochloride serves as a diuretic, aiding in the increase of urine output and helping to remove excess water and salts from the body, which can be beneficial in treating conditions like edema and high blood pressure.
Used in Antihypertensive Therapy:
3-(aminomethyl)benzenesulfonamide hydrochloride is utilized as an antihypertensive agent, contributing to the reduction of blood pressure by promoting the excretion of excess fluid and salts, thus helping to manage hypertension effectively.

Check Digit Verification of cas no

The CAS Registry Mumber 670280-13-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,0,2,8 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 670280-13:
(8*6)+(7*7)+(6*0)+(5*2)+(4*8)+(3*0)+(2*1)+(1*3)=144
144 % 10 = 4
So 670280-13-4 is a valid CAS Registry Number.

670280-13-4Downstream Products

670280-13-4Relevant academic research and scientific papers

PRO-DRUG FORMING COMPOUNDS

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Page/Page column 31, (2015/02/02)

Various prodrug compounds having the general structure: Active agent- (acid)-(linker) - SO2NR1R2 are described herein. Compounds having this general structure were shown to be more orally active than the unmodified parent molecule.

2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS

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Page/Page column 86, (2010/04/03)

Pyrido(3,2-d)pyrimidine derivatives represented by the structural formuia (Ia): wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro

Multicyclic bis-amide MMP inhibitors

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Page/Page column 86-87, (2008/06/13)

The present invention relates generally to bis-amide group containing pharmaceutical agents, and in particular, to multicyclic bis-amide MMP-13 inhibitor compounds. More particularly, the present invention provides a new class of MMP-13 inhibiting compounds, containing a pyrimidinyl bis-amide group in combination with a heterocyclic moiety, that exhibit an increased potency and solubility in relation to currently known bis-amide group containing MMP-13 inhibitors.

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