67029-84-9

Usage

Uses

Used in Pharmaceutical Research:
6-Chloro-7-methylchromone is utilized as a pharmaceutical candidate for its anti-inflammatory properties, offering potential benefits in the treatment of inflammatory conditions by reducing inflammation and associated symptoms.
Used in Antioxidant Applications:
As an antioxidant, 6-CHLORO-7-METHYLCHROMONE is employed to combat oxidative stress and protect cells from damage caused by reactive oxygen species, which can contribute to various diseases and aging processes.
Used in Antimicrobial Research:
6-CHLORO-7-METHYLCHROMONE is used as an antimicrobial agent, demonstrating potential in fighting against microbial infections by inhibiting the growth of bacteria, fungi, or other microorganisms.
Used in Cancer Research:
In the field of cancer research, 6-CHLORO-7-METHYLCHROMONE is used as a potential drug candidate for its possible role in targeting cancer cells, with the aim of developing new therapeutic strategies for cancer treatment.
Used in Medical Condition Treatment:
6-CHLORO-7-METHYLCHROMONE is explored for its potential use in treating various medical conditions, leveraging its multifaceted biological activities to address a range of health issues.

InChI:InChI=1/C10H9ClO2/c1-6-4-10-7(5-8(6)11)9(12)2-3-13-10/h4-5H,2-3H2,1H3

Upstream product

• 1367517-28-9 (E)-1-(5-chloro-2-hydroxy-4-methylphenyl)-3-(dimethylamino)prop-2-en-1-one 
• 28480-70-8 5'-chloro-2'-hydroxy-4'-methyl acetophenone 
• 109-94-4 formic acid ethyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 147919-55-9 6-Chloro-7-methyl-2-phenyl-chroman-4-one 

Relevant academic research and scientific papers

Substituent-Oriented Synthesis of Substituted Pyrazoles/Chromeno[3,2- c]pyrazoles via Sequential Reactions of Chromones/3-Chlorochromones and Tosylhydrazones

A facile and efficient synthetic strategy for the chemoselective synthesis of monocyclic/tricyclic-fused pyrazoles was developed, and it was oriented by different 3-position substituents (H or Cl) on the chromones. The reaction proceeded in a one-pot sequential way with a broad substrate scope and moderate to excellent yields.

Rhodium/chiral diene-catalyzed asymmetric 1,4-addition of arylboronic acids to chromones: A highly enantioselective pathway for accessing chiral flavanones

Chromone has been noted to be one of the most challenging substrates in the asymmetric 1,4-addi-tion of α,β-unsaturated carbonyl compounds. By employing the rhodium complex associated with a chiral diene ligand, (R,R)-Ph-bod, the 1,4-addition of a variety of aryl-boronic acids was realized to give high yields of the corresponding flavanones with excellent enantioselectivities (≥97% ee, 99% ee for most substrates). Ring-opening side products, which would lead to erosion of product enantioselectivity, were not observed under the stated reaction conditions.

2,3-Unsubstituted chromones and their enaminone precursors as versatile reagents for the synthesis of fused pyridines

A divergent and regioselective approach to fused pyridines was developed through formal [3 + 3] cyclocondensations from simple 2,3-unsubstituted chromones or their enaminone precursors.