67035-76-1

Upstream product

• 141990-96-7 [3-(6H-dibenzo[b,e]oxepin-11-ylidene)-propyl]-methyl-carbamic acid 2,2,2-trichloro-ethyl ester 
• 1229-29-4 doxepin hydrochloride 
• 1668-19-5 doxepin 
• 3607-34-9 (E)-doxepin 
• 127347-16-4 (E)-11-(3-N,N-dimethylaminopropylidene)-6H,11H-dibenzooxepin maleat 
• 4504-87-4 6,11-dihydrodibenz[b,e]oxepin-11-one 

Downstream Products

• 4504-96-5 desmethyldoxepin hydrochloride salt 
• 124694-01-5 E-3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-N-[4-[4-(1,1-dimethylethyl)phenyl]-4-oxobutyl]-1-propanamine hydrochloride 

Relevant academic research and scientific papers

N-DESMETHYL-DOXEPIN AND METHODS OF USING THE SAME TO TREAT SLEEP DISORDERS

The invention relates to desmethyldoxepin, isomers of desmethyldoxepin, and pharmaceutically acceptable salts and prodrugs of desmethyldoxepin; compositions containing the same, and the use of any of the aforementioned for the treatment of sleep disorders.

Methods of using low-dose doxepin for the improvement of sleep

Methods of preventing early awakenings, and improving sleep efficiency in hours 7 and 8 of a period of sleep, by administration of low doses of doxepin (e.g., 1-6 mg).