67036-08-2Relevant academic research and scientific papers
Copper-Mediated Deacylative Coupling of Ynones via C-C Bond Activation under Mild Conditions
Feng, Lili,Hu, Tingjun,Zhang, Saisai,Xiong, Heng-Ying,Zhang, Guangwu
supporting information, p. 9487 - 9492 (2019/12/02)
The intermolecular deacylative coupling of unstrained ynones via C-C bond activation was accomplished by a CuCl-bpy system under mild reaction conditions. This protocol features facile cleavage of the C-C bond at room temperature, broad substrate scope, and efficient construction of important symmetric and unsymmetrical 1,3-diyne adducts through homo or cross coupling of ynones, respectively. The preliminary mechanistic investigations indicated that an acyl copper(III) complex is likely involved in this process.
Selective Reductions. 52. Efficient Asymmetric Reduction of α-Acetylenic α'-Fluoroalkyl Ketones with Either B-Chlorodiisopinocampheylborane or B-Isopinocampheyl-9-borabicyclononane in High Enantiomeric Purity. The Influence of Fluoro Groups in Such
Ramachandran, P. Veeraraghavan,Gong, Baoqing,Teodorovic, Aleksandar V.,Brown, Herbert C.
, p. 1061 - 1074 (2007/10/02)
A systematic study of the asymmetric reduction of prochiral α-acetylenic α'-fluoroalkyl ketones with (-)-B-chlorodiisopinocampheylborane and (-)-B-isopinocampheyl-9-borabicyclononane (R-Alpine-Borane, 2) reveals that perfluoro
