67048-54-8

Upstream product

• 17452-79-8 5-(4-chlorophenyl)-1,3,4-oxathiazol-2-one 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 73501-05-0 5-(p-chlorophenyl)-2,2-bis(trichloromethyl)-1,3,4-oxathiazole 
• 15965-44-3 3-(4-chloro-phenyl)-[1,4,2]dithiazol-5-one 
• 15965-41-0 3-(p-chlorophenyl)-1,4,2-dithiazole-5-thione 
• 2521-24-6 4-chlorothiobenzamide 
• 619-56-7 4-chlorobenzamide 

Downstream Products

• 67048-76-4 3-(4-chlorophenyl)-1,2-thiazole-4,5-dicarboxylic acid 
• 19762-93-7 3-(4-chlorophenyl)-1,2-thiazole-4-carboxylic acid 
• 67048-37-7 ethyl 3-(4-chlorophenyl)-1,2-thiazole-4-carboxylate 

Relevant academic research and scientific papers

ISOTHIAZOLE AND PYRAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS

The present invention relates to isothiazole and pyrazole compounds of formula (I) having plant growth regulating properties, to agricultural compositions comprising them, and to the use of said compounds for regulating plant growth.

ISOTHIAZOLE AND PYRAZOLE DERIVATIVES AS FUNGICIDES

The present invention relates to compounds of Formula (I) wherein R1, R2, R3 or R4 are as defined in claim 1 or a salt or N-oxide thereof and their use in methods for the control and/or prevention of fungal infe

Nitrile Sulphides. Part 3. Thermal Fragmentation of 1,3,4-Oxathiazoles: Formation of Nitrile Sulphides in a Retro-1,3-dipolar Cycloaddition Reaction

On thermolysis at ca. 160 gradC 1,3,4-oxathiazoles undergo retro-1,3-dipolar cycloaddition forming nitrile sulphides and carbonyl-containing fragments.The nitrile sulphides either decompose to sulphur and nitriles or are trapped as their 1,3-dipolar cycloadducts in the presence of dipolarophiles (dimethyl acetylenedicarboxylate, ethyl cyanoformate, benzonitrile, ethyl propiolate).Similar ratios (1.32, l.34, 1.33, 1.31) of 4- and 5-ethoxycarbonyl-3-(p-methoxyphenyl)isothiazole obtained from four sources of p-methoxybenzonitrile sulphide with ethyl propriolate provide strong evidence for product formation from a discrete intermediate nitrile sulphide rather than via direct interaction of precursor with dipolarophile. 2-Dichloromethylene-1,3,4-oxathiazoles, prepared by dehydrochlorination of 2-trichloromethyloxathiazoles, prepared by dehydrochlorination of 2-trichlorometyloxathiazoles, likewise fragment to nitrile sulphides, but attempts to trap dichloroketene were unsuccessful.

THE THERMAL FRAGMENTATION OF 1,3,4-DITHIAZOL-2-ONES

Thermal expulsion of carbon oxysulphide from 1,3,4-dithiazol-2-ones in the presence of DMAD affords nitrile sulphide-derived dimethyl isothiazole-4,5-dicarboxylates.

Nitrile Sulphide Formation from the Thermal Fragmentation of 1,3,4-Oxathiazoles: a Retro-1,3-dipolar Cycloaddition

1,3,4-Oxathiazoles, on thermolysis, undergo retro-1,3-dipolar cycloaddition to afford carbonyl compounds and nitrile sulphides, which may be trapped by cycloaddition with alkynes and nitriles.