67051-21-2 Usage
Class of Medication
Hydantoin anticonvulsant
Therapeutic Use
Treatment of epilepsy and seizures
Mechanism of Action
Stabilizes electrical activity in the brain, preventing seizures
Forms Available
Tablets, capsules, suspension
Administration Route
Oral (taken by mouth)
Therapeutic Index
Relatively narrow, necessitating blood level monitoring
Adverse Effects
Dizziness, drowsiness, nausea, among others
Importance
Significant medication for managing specific types of seizures and epilepsy
Check Digit Verification of cas no
The CAS Registry Mumber 67051-21-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,0,5 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67051-21:
(7*6)+(6*7)+(5*0)+(4*5)+(3*1)+(2*2)+(1*1)=112
112 % 10 = 2
So 67051-21-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H20N2O3/c1-2-3-4-8-11-16(12-9-6-5-7-10-12)13(19)17-15(21)18-14(16)20/h5-7,9-10H,2-4,8,11H2,1H3,(H2,17,18,19,20,21)
67051-21-2Relevant articles and documents
Novel 5,5-disubstitutedpyrimidine-2,4,6-triones as selective MMP inhibitors
Foley, Louise H,Palermo, Robert,Dunten, Pete,Wang, Ping
, p. 969 - 972 (2007/10/03)
The 5,5-disubstitutedpyrimidine-2,4,6-triones represent a new class of MMP inhibitors showing selectivity for the gelatinases A and B, collagenase-3, and human neutrophil collagenase. The SAR presented here is in good agreement with an X-ray structure of compound 5 bound to the catalytic domain of stromelysin-1. While of the barbiturate structural class, compound 5 did not show any toxic or sedative effects.
