6708-37-8

Basic information

• Product Name: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride
• Synonyms: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride;6-Endoethylene-4-cyclohexene-1,2-dicarboxylic anhydride;Bicyclo[2.2.2]OCL-5-Ene-2,3-Dicarboxylic Anhydride;Bicylo[2,2,2]oct-5-ene-2,3-dicarboxylic anhydride;endo-bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid anhydride
• CAS NO: 6708-37-8
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.18
• Mol File: 6708-37-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 148 °C
• Boiling Point: 340.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.324
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: soluble in Acetone
• CAS DataBase Reference: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride(6708-37-8)
• EPA Substance Registry System: bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride(6708-37-8)

Safety Data

• Hazardous Substances Data: 6708-37-8(Hazardous Substances Data)

Usage

General Description

Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride is a chemical compound with a bicyclic structure and two carboxylic acid groups. It is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and polymers. The anhydride form of the compound is highly reactive and is often used as a crosslinking agent in the production of epoxy resins and as a curing agent for various polymers. It can also be used as a hardener for epoxy resins, an antioxidant in plastics, and a reactive diluent in adhesives and coatings. Additionally, it is employed as an intermediate in the synthesis of a wide range of fine chemicals due to its versatile reactivity and structural features.

Upstream product

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Downstream Products

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• 1630906-99-8 cis-3-aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester hydrochloride 
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Relevant articles and documents

PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES

Pharmaceutical compositions containing di, tri, and tetracyclic acylhydrazide derivatives of the formula below, for use in the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.

Photochemisch induzierte exo-selektive Diels-Alder-Reaktionen

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Synthesis of exo-Bicyclooct-5-ene-dicarboxylic Anhydrides by Thermal Isomerization of trans-Diacids

Bicyclooct-5-ene-trans-1,2-dicarboxylic acid and substituted analogues afford mixtures of the corresponding exo- and endo-anhydrides upon heating at 250-300 deg C.This isomerization provides a practical pathway to substituted and deuterium-labeled exo-anhydrides which are otherwise difficult to obtain.A mechanistic study shows that retro-diene fragmentation is not involved in the isomerization.