67086-82-2Relevant academic research and scientific papers
Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias
Jackson, Chris M.,Blass, Benjamin,Coburn, Keith,Djandjighian, Laurent,Fadayel, Gina,Fluxe, Andrew J.,Hodson, Steven J.,Janusz, John M.,Murawsky, Michael,Ridgeway, James M.,White, Ronald E.,Wu, Shengde
, p. 282 - 284 (2007/10/03)
Blockade of the Kv1.5 ion channel is a potentially atrial-selective avenue for the treatment of atrial fibrillation and atrial flutter. The development and biological evaluation of a series of thiazolidine-based blockers of Kv1.5 is described.
Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof
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, (2008/06/13)
New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: STR1 wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C1-4 -alkyl, C1-4 -alkoxy, halo-C1
Comparative radioprotective activity of various pentagonal compounds with two heteroatomes
Robbe,Fernandez,Dubief,et al.
, p. 235 - 243 (2007/10/02)
Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.
2-Phenyl thiazolidine derivatives as radioprotective agents
Terol,Fernandez,Robbe,et al.
, p. 149 - 151 (2007/10/04)
31 derivatives of 2-phenyl thiazolidine were submitted to radio-pharmacological tests on mice. They usually present little toxicity and some of them show a rather interesting activity.
