67093-66-7

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 370867-98-4 (E)-3-[2-(diphenylphosphanyl)benzoyloxy]-5-phenyl-pent-4-enoic acid tert-butyl ester 
• 136031-71-5 tert-butyl (3R,4E)-3-hydroxy-5-phenyl-4-pentenoate 
• 120823-67-8 tert-butyl (E,E)-5-phenylpenta-2,4-dienoate 
• 1454283-61-4 tert-butyl 3-styryl-2H-azirine-2-carboxylate 
• 1454283-83-0 5-tert-butyl 2-ethyl 4-phenyl-6-styrylpyridine-2,5-dicarboxylate 
• 1127435-37-3 tert-butyl (4E)-3-carbonyl-5-phenyl-4-pentenoate 

Relevant academic research and scientific papers

Synthesis of pyridines by carbenoid-mediated ring opening of 2H-azirines

Roaming the range: The title reaction tolerates a wide range of substituents on the resulting pyridine ring using mild reaction conditions (see scheme; esp=α,α,α′,α′-tetramethyl-1,3- benzenedipropionic acid). The formation of the key intermediate is catal

Reformatsky reactions with SmI2 in catalytic amount

A substoichiometric protocol for Reformatsky-type addition of α-haloesters, α-haloketones, α-halonitriles, and α-halophosphonates to carbonyl compounds has been developed. β-Hydroxyesters and β-hydroxynitriles were obtained in good to excellent yields.