67111-66-4

Basic information

• Product Name: (1R)-(+)-CAMPHANIC ACID
• Synonyms: (+)-CAMPHANIC ACID;(1R)-(+)-CAMPHANIC ACID;(1R)-3-OXO-4,7,7-TRIMETHYL-2-OXABICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID;2-Oxabicyclo2.2.1heptane-1-carboxylic acid, 4,7,7-trimethyl-3-oxo-, (1R,4S)-;D-(1S,3R)-(-)-CAMPHORIC ACID;(1R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid, (1R)-3-Oxo-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid;(1R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid;(1S,4R)-1,7,7-trimethyl-2-oxo-3-oxabicyclo[2.2.1]heptane-4-carboxylic acid
• CAS NO: 67111-66-4
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.22
• Product Categories: Chiral Compound
• Mol File: 67111-66-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 200-202 °C(lit.)
• Boiling Point: 355.5 °C at 760 mmHg
• Flash Point: 142.1 °C
• Appearance: /
• Density: 1.296 g/cm³
• Vapor Pressure: 5.19E-06mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: 2-8°C
• PKA: 3.36±0.60(Predicted)
• CAS DataBase Reference: (1R)-(+)-CAMPHANIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-(+)-CAMPHANIC ACID(67111-66-4)
• EPA Substance Registry System: (1R)-(+)-CAMPHANIC ACID(67111-66-4)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 67111-66-4(Hazardous Substances Data)

Usage

Uses

Chiral auxiliary in the synthesis of azasugars.

InChI:InChI=1/C10H14O4/c1-8(2)9(3)4-5-10(8,6(11)12)14-7(9)13/h4-5H2,1-3H3,(H,11,12)/t9-,10+/m1/s1

Upstream product

• 87859-84-5 (-)-(1R,3R)-3-chlorocamphoric anhydride 
• 432036-82-3 (-)-(1S,4R)-camphanic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 432036-81-2 (-)-(1S,4R)-camphanic acid [(5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 48138-74-5 1,2,2-trimethyl-cyclopentane-1,3-dicarbonyl chloride 
• 87859-83-4 α-chlorocamphoric acid dichloride 
• 124-83-4 D-(+)-camphoric acid 
• 88701-62-6 1-(Cyanovinyl) (1'S)-camphanate 
• 39637-74-6 (1S)-(-)-camphanic chloride 
• 88764-13-0 (1R,2R,4R)-2-exo-cyano-7-oxabicyclo<2.2.1>hept-5-en-2-endo-yl(1S)-camphanate 
• 10333-96-7 1-Bromo-5,8,8-trimethyl-3-oxa-bicyclo[3.2.1]octane-2,4-dione 
• 124-83-4 (+)-camphoric acid 

Downstream Products

• 138403-92-6 (R)-Methoxy-phenyl-acetic acid (4bR,8aR,9R)-7-[1-ethoxycarbonyl-meth-(E)-ylidene]-2-methoxy-4b,5,6,7,8,8a,9,10-octahydro-phenanthren-9-yl ester 
• 133098-41-6 4'-N-camphanyl-(4'R)-<4-2H1>-3,5'-O-dibenzylpyridoxamine 
• 133008-70-5 4'-N-camphanyl-(4'S)-<4-2H1>-3,5'-O-dibenzylpyridoxamine 
• 133008-61-4 (4'R)-<4'-2H1>-3,5'-O-dibenzylpyridox-4'-yl camphanate 
• 133098-40-5 (4'S)-<4'-2H1>-3,5'-O-dibenzylpyridox-4'-yl camphanate 
• 142696-11-5 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 1-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl]-1H-pyrrol-2-ylmethyl ester 
• 142597-20-4 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 1-[(S)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl]-1H-pyrrol-2-ylmethyl ester 
• 39637-74-6 (-)-ω-camphanic acid chloride 
• 84064-04-0 (-)-methyl 4-<3-<3-<2-<1-<(1S)-ω-camphanyloxy>cyclohexyl>ethyl>-4-oxo-2-thiazolidinyl>propyl>benzoate 
• 84040-69-7 (+)-methyl 4-<3-<3-<2-<1-<(1S)-ω-camphanyloxy>cyclohexyl>ethyl>-4-oxo-2-thiazolidinyl>propyl>benzoate 
• 39637-74-6 (1S)-(-)-camphanic chloride 
• 245655-52-1 (1R)-3,4-dehydrocamphoroyl difluoride 
• 245655-48-5 (1R,4S)-camphanoyl fluoride 
• 245655-46-3 (1R,4S)-(-)-3-oxa-4-trifluoromethylcamphor 

Relevant articles and documents

Practical synthesis of PGI2 agonist: Resolution-inversion- recycle approach of its chiral intermediate

Practical synthesis of ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4- tetrahydronaphth-2-yl)methanol ((R)-7b), a key chiral intermediate for the synthesis of the novel PGI2 agonist, (R)-[6-[(diphenylcarbamoyloxy) methyl]-6-hydroxy-5,6,7,8-tetrahydronapht

(-)-(1S,4R)-camphanoyl chloride

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Carotenoids and Related Compounds. Part 37. Stereochemistry and Synthesis of Capsorubin

The two oxygen substitutents in the end groups of capsorubin were shown to be trans to one another by synthesis of optically inactive forms of the carotenoid, and of the isomers which have the corresponding cis-structure.The 3S,5R,3'S,5'R configuration thus established for the natural carotenoid was confirmed by synthesis of this stereoisomer from (+)-camphor.Cryptocapsin has the 3'S,5'R configuration, and the racemic form has been synthesised.Capsanthin has the 3R,3'S,5'R configuration.