67119-49-7Relevant academic research and scientific papers
Rapid reduction of heteroaromatic nitro groups using catalytic transfer hydrogenation with microwave heating
Quinn, John F.,Bryant, Cole E.,Golden, Kathryn C.,Gregg, Brian T.
experimental part, p. 786 - 789 (2010/03/24)
A method for the rapid, safe reduction of heteroaromatic and aromatic nitro groups to amines is described using catalytic transfer hydrogenation under microwave heating conditions. Commonly available Pd/C or Pt/C catalyst is extremely effective with 1,4-cyclohexadiene as the hydrogen transfer source. In the case of substrates containing potentially labile aromatic halogens, Pt/C is effective and results in little or no dehalogenation. In general, the reactions are complete within 5 min at 120 °C.
A novel strategy for the preparation of arylhydroxylamines: Chemoselective reduction of aromatic nitro compounds using bakers' yeast
Li, Feng,Cui, Jingnan,Qian, Xuhong,Zhang, Rong
, p. 2338 - 2339 (2007/10/03)
Using bakers' yeast as a biocatalyst, the chemoselective reduction of aromatic nitro compounds bearing electron-withdrawing groups gave the corresponding hydroxylamines with good to excellent conversion under mild conditions.
A convenient sonochemical synthesis of vicinally substituted 3-hydroxylaminopyridines
Rusinov, G. L.,Filatov, I. E.,Pashkevich, K. I.
, p. 325 - 327 (2007/10/02)
A method of synthesis of vicinally substituted N-(3-pyridyl)hydroxylamines by reducing the corresponding nitropyridines with Zn/NH4Cl/EtOH under ultrasonication is proposed.Ultrasound irradiation increases the yields of these hydroxylamines and facilitates their isolation.
