67119-85-1

Basic information

• Product Name: (+/-)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enone
• Synonyms: (+/-)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enone
• CAS NO: 67119-85-1
• Molecular Weight: 154.209
• Mol File: 67119-85-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+/-)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enone(67119-85-1)
• EPA Substance Registry System: (+/-)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enone(67119-85-1)

Safety Data

• Hazardous Substances Data: 67119-85-1(Hazardous Substances Data)

Upstream product

• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 488787-31-1 6-[(1-hydroxy-1-methyl)ethyl]-3-ethoxy-2-cyclohexen-1-one 
• 67119-82-8 1-(2-Methoxy-4-trimethylsilanyloxy-cyclohex-3-enyl)-ethanone 
• 917-64-6 methyl magnesium iodide 
• 104841-04-5 2-(2-Methoxy-4-trimethylsilanyloxy-cyclohex-3-enyl)-propan-2-ol 

Downstream Products

• 80113-04-8 (+/-)-1-(1,3-dithianyl)-4-(1-hydroxy-1-methylethyl)cyclohex-2-enol 
• 488787-45-7 (R)-4-[(1-hydroxy-1-methyl)ethyl]-2-cyclohexen-1-one 
• 136954-91-1 (+/-)-11-oxo-Δ⁹-tetrahydrocannabiol tert-butyldimethylsilyl ether 
• 123331-92-0 2-((1R,6R)-3-[1,3]Dithian-2-yl-6-isopropenyl-cyclohex-2-enyl)-5-pentyl-benzene-1,3-diol 
• 52663-85-1 11-oxo-6a,10a-trans-Δ⁹-THC 
• 28623-60-1 (+/-)-11-hydroxy-Δ⁹-tetrahydrocannabinol 

Relevant articles and documents

Cannabidiol derivative as well as preparation method and medical application thereof

The invention relates to a cannabidiol derivative and application thereof in medicine, in particular to a pyrimidine derivative as shown in a general formula (I), or a stereoisomer, a solvate, a metabolite, a prodrug, a pharmaceutically acceptable salt or a co-crystal thereof, and definition of each substituent in the general formula (I) is the same as that in the specification.

Synthesis of Racemic and Optically Active Δ9-Tetrahydrocannabinol (THC) Metabolites

The preparation of racemic and optically active Δ9-THC metabolites is described from synthon 13.Racemic synthon 13 is prepared in four steps (46percent) from Danishefsky's diene.Optically active synthon 13 is prepared from perillaldehyde via the enone 22 in six steps (23percent yield).Alternatively, nopinone can be converted to 13 in three steps (50percent yield) via a cyclobutane ring cleavage.The acid-catalyzed condensation of 13 with olivetol (6a) and subsequent conversion to 11-hydroxy and 9-carboxyl Δ9-THC metabolites 2a and 4a is described, as well as the preparation of 1',1'-dimethylheptyl THC analogues 2b, 3b, and 4 b from 5-(1',1'-dimethylheptyl)resorcinol (6c).