67127-79-1

Downstream Products

• 67324-88-3 3-acetyl-5-fluoro-2-hydroxy-N-(1⁽²⁾H-tetrazol-5-yl)-benzamide 
• 1289079-82-8 3-[3-(2,3-dichlorophenyl)-acryloyl]-5-fluoro-2-hydroxybenzoic acid 
• 1289079-80-6 3-[3-(2,4-dichlorophenyl)-acryloyl]-5-fluoro-2-hydroxybenzoic acid 
• 1289079-78-2 3-[3-(4-chlorophenyl)-acryloyl]-5-fluoro-2-hydroxybenzoic acid 
• 1289079-86-2 5-fluoro-2-hydroxy-3-[3-(2,3,5-trichlorophenyl)-acryloyl]benzoic acid 
• 1289080-36-9 3-[3-(2,5-dichlorophenyl)propionyl]-5-fluoro-2-hydroxybenzoic acid 
• 1289079-88-4 5-fluoro-2-hydroxy-3-[3-(2,3,6-trichlorophenyl)-acryloyl]benzoic acid 
• 1289079-84-0 3-[3-(2,5-dichlorophenyl)-acryloyl]-5-fluoro-2-hydroxybenzoic acid 
• 187272-80-6 3'-carboxy-5'-fluoro-2'-hydroxy-3-[2-(2-quinolinyl)ethenyl]chalcone 

Relevant academic research and scientific papers

Flavone derivative and medicine comprising the same

This invention relates to a flavone derivative represented by the formula (1) or a salt thereof, and also to a medicine containing the same. wherein A represents H, halogen, phenyl, naphthyl, a group of the formula (2) in which X is H or halogen, B is -CH

Chalcone derivatives and drugs containing the same

PCT No. PCT/JP97/01652 Sec. 371 Date Nov. 17, 1998 Sec. 102(e) Date Nov. 17, 1998 PCT Filed May 16, 1997 PCT Pub. No. WO97/44306 PCT Pub. Date Nov. 27, 1997This invention relates to chalcone derivatives represented by the following formula (1): wherein A represents a phenyl group, a quinolyl group or the like, W represents a vinylene group or the like, and R1 to R5 each independently represent a carboxyl, cyano, alkyloxycarbonyl or like group, or salts of the chalcone derivatives, and also to drugs containing them as effective ingredients. These compounds have excellent cys-LT receptor antagonism, and are useful as antiallergic agents or the like.

Benzamide derivatives

Benzamide derivatives of the formula:- STR1 wherein R1 represents a fluorine, chlorine or bromine atom, or an alkyl, alkoxy, alkylthio, alkylsulphonyl, alkanoylamino, alkylamino or alkylsulphamoyl group, each such group containing from 1 to 6 carbon atoms, a dialkylsulphamoyl, dialkylamino or dialkylcarbamoyl group (wherein the two alkyl groups may be the same or different and each contains from 1 to 4 carbon atoms), an alkanoyl, alkoxycarbonyl, alkoxycarbonylamino or alkylcarbamoyl group containing from 2 to 6 carbon atoms, or a hydroxy, formyl, nitro, trifluoromethyl, aryl, benzyloxycarbonylamino, amino, sulphamoyl, cyano, tetrazol-5-yl, carboxy, carbamoyl or aroyl group, and n represents an integer 1, 2 or 3, are new compounds possessing pharmacological properties, in particular properties of value in the treatment of respiratory disorders manifested by the interaction of tissue-fixed antibodies with specific antigens.