6713-03-7

Usage

Chemical Properties

Colorless Oil

Uses

Hydroxyethylthio Propanol (cas# 6713-03-7) is a compound useful in organic synthesis.

InChI:InChI=1/C5H12O2S/c1-5(7)4-8-3-2-6/h5-7H,2-4H2,1H3

Upstream product

• 60-24-2 2-hydroxyethanethiol 
• 127-00-4 1-Chloro-2-propanol 
• 75-56-9 methyloxirane 

Downstream Products

• 32014-03-2 1-(2-hydroxy-ethanesulfonyl)-propan-2-ol 
• 23256-30-6 nifurtimox 
• 26494-77-9 methyl-3 amino-4 thiomorpholine dioxyde-1,1 
• 39093-59-9 6-phenoxy-3-thiahexan-1,5-diol 
• 75-56-9 methyloxirane 
• 75-21-8 oxirane 
• 42589-17-3 β-Hydroxypropyl-β-hydroxy-γ-phenoxypropylsulfid 
• 26475-39-8 2-methyl-1,4-oxathiane 4,4-dioxide 

Relevant academic research and scientific papers

Efficient synthesis of β, β'-dihydroxy sulfides by ring opening of epoxides with mercaptoethanol catalyzed under solvent-free conditions

A simple and highly efficient synthesis of β, β′-dihydroxy sulfides has been achieved by ring opening of epoxides with mercaptoethanol using catalytic amount of benzyltrimethylammonium hydroxide (Triton B) under solvent-free conditions. Excellent regioselectivity was found for aliphatic unsymmetrical epoxides, with nucleophilic attack at the less-hindered carbon atom of the epoxide. However, this regioselectivitywas not observed for styrene oxide and a mixture of two isomers was obtained. This process was also regio- and chemo-selective as illustrated using epichlorohydrin with two epoxide ring positions and mercaptoethanol with two functional groups (SH and OH). Figure Presented.

N-AMINO TETRAHYDROTHIAZINE DERIVATIVES, METHOD OF MANUFACTURE AND USE

This invention comprises the innovative synthesis of N-amino tetrahydrothiazine free bases and their salts. This invention further comprises the use of the derivatives and their therapeutic application as anticancer agents. Further this invention comprises their manufacture and use.

NITROFURAN COMPOUNDS FOR THE TREATMENT OF CANCER AND ANGIOGENESIS

The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The invention also provides compositions, unit dosage forms, and kits comprising the compounds.