67130-86-3Relevant academic research and scientific papers
3-heterocyclylpropanohydroxamic acid PCP inhibitors
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, (2008/06/13)
Compounds of formula (I): and their salts, solvates, hydrates and prodrugs are useful PCP inhibitors, processes for making the same, compositions comprising the same, and methods of treating a PCP-mediated condition or disease using the same.
N-[(5-Halo-2,6-(substituted)pyrazinyl)methylene]amine antimicrobial compounds, compositions and use
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, (2008/06/13)
Antimicrobial compounds of the formula: STR1 wherein: Hal is bromine or chlorine; and R is halo; mono- or di-substituted mono- or diloweralkylamino wherein the loweralkyl substituents are hydroxy or loweralkanoyloxy; 4-morpholino; thiocyano; mercapto; straight or branched chain C1-8 alkylthio; mono- or di-substituted loweralkylthio wherein the substituents are hydroxy, amino, loweralkanoylamino, or loweralkoxycarbonyl; arylthio; loweralkylsulfoxy; or loweralkylsulfonyl; R1 is hydrogen; or loweralkyl; R2 is (CH2)n COORa, where Ra is hydrogen, loweralkyl, or benzyl; and n is 1 to 3; R1 and R2 are taken together with an oxygen or nitrogen atom or form morpholino, piperazinyl, or piperazinyl which is N-loweralkyl substituted; R3 is hydrogen; straight or branched C1-8 alkyl; aryl; aryl substituted with up to two members selected from the group consisting of C1-3 alkyl, C1-3 alkoxy, halo, and mono- or di-C1-3 alkyl substituted amino; heteroaryl; formylC2-4 alkenyl; or C2-4 alkenyl; and R4 is straight or branched C1-8 alkyl; loweralkoxy; hydroxy; loweralkoxycarbonylmethyl; benzyl; or benzyl substituted with up to two members selected from the group consisting of halo, loweralkyl, and loweralkoxy; are useful in various agricultural and industrial applications.
3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use
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, (2008/06/13)
Antimicrobial compounds of the formula: STR1 wherein: Hal is bromine or chlorine; and R is halo; mono- or di-substituted mono- or diloweralkylamino wherein the loweralkyl substituents are hydroxy or loweralkanoyloxy; 4-morpholino; thiocyano; mercapto; straight or branched chain C1-8 alkylthio; mono- or di-substituted loweralkylthio wherein the substituents are hydroxy, amino, loweralkanoylamino, or loweralkoxycarbonyl; arylthio; loweralkylsulfoxy; or loweralkylsulfonyl; R1 is hydrogen; or loweralkyl; R2 is hydroxyloweralkyl; (CH2)n COORa, where Ra is hydrogen, loweralkyl, or benzyl; and n is 1 to 3; R1 and R2 are taken together with an oxygen or nitrogen atom to form morpholino, piperazinyl, or piperazinyl which is N-loweralkyl substituted; and R3 is hydrogen; straight or branched C1-8 alkyl, provided that when R3 is hydrogen or C1-8 alkyl, R is other than halo; aryl; aryl substituted with up to two members selected from the group consisting of C1-3 alkyl, C1-3 alkoxy, halo, and mono- or di-C1-3 alkyl substituted amino; heteroaryl; formyl C2-4 alkenyl; or C2-4 alkenyl; are useful in various agricultural and industrial applications.
2-(Substituted)amino-3-cyano-5-halo-6-(substituted)-pyrazine antimicrobial compounds, compositions and use
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, (2008/06/13)
Antimicrobial compounds of the formula: STR1 wherein: Hal is bromine or chlorine; and R is halo; mono- or di-substituted mono- or diloweralkylamino wherein the loweralkyl substituents are hydroxy or loweralkanoyloxy; 4-morpholino; thiocyano; mercapto; straight or branched chain C1-8 alkylthio; mono- or di-substituted loweralkylthio wherein the substituents are hydroxy, amino, loweralkanoylamino, or loweralkoxycarbonyl; arylthio; loweralkylsulfoxy; or loweralkylsulfonyl; R1 is hydrogen; or loweralkyl; R2 is (CH2)n COOR3, where R3 is hydrogen, loweralkyl, or benzyl; and n is 1 to 3; and R1 and R2 are taken together with an oxygen or nitrogen atom to form morpholino, piperazinyl, or piperazinyl which is N-loweralkyl substituted; are useful in various agricultural and industrial areas.
