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6714-05-2

D-Homoestradiol, also known as dihydroestradiol, is a naturally occurring metabolite of estradiol, the primary female sex hormone. It is formed through the reduction of the double bond between carbons 1 and 2 in the A-ring of estradiol, resulting in a more stable and less potent compound. D-Homoestradiol plays a role in the regulation of estrogen levels in the body and has been implicated in various physiological processes, including bone metabolism and the development of certain cancers. However, its exact functions and mechanisms of action are not yet fully understood, and further research is needed to elucidate its role in human health and disease.

6714-05-2

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6714-05-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6714-05-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,1 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6714-05:
(6*6)+(5*7)+(4*1)+(3*4)+(2*0)+(1*5)=92
92 % 10 = 2
So 6714-05-2 is a valid CAS Registry Number.

6714-05-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,17aβ-dihydroxy-D-homoestra-1,3,5(10)-triene

1.2 Other means of identification

Product number -
Other names (4bS)-2.7t-Dihydroxy-6at-methyl-(4brH.10acH.10btH)-4b.5.6.6a.7.8.9.10.10a.10b.11.12-dodecahydro-chrysen

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6714-05-2 SDS

6714-05-2Downstream Products

6714-05-2Relevant articles and documents

Syntheses and antiproliferative effects of d-homo- and d-secoestrones

Mernyák, Erzsébet,Szabó, Johanna,Bacsa, Ildikó,Huber, Judit,Schneider, Gyula,Minorics, Renáta,Bózsity, Noémi,Zupkó, István,Varga, Mónika,Bikádi, Zsolt,Hazai, Eszter,W?lfling, János

, p. 128 - 136 (2014/07/21)

Substituted and/or heterocyclic d-homoestrone derivatives were synthetized via the intramolecular cyclization of a δ-alkenyl-d-secoaldehyde, -d-secoalcohol or -d-secocarboxylic acid of estrone 3-benzyl ether. The d-secoalcohol was modified at three sites in the molecule. The in vitro antiproliferative activities of the new d-homo- and d-secoestrone derivatives were determined on HeLa, MCF-7, A431 and A2780 cells through use of MTT assay. d-Homoalcohols 3 and 5 displayed cell line-selective cytostatic effects against ovarian and cervical cell lines, respectively. Two d-secoestrones (6 and 12c) proved to be effective, with IC50 values comparable with those of the reference agent cisplatin. A selected compound (6) was tested by tubulin polymerization assay and its cancer specificity was additionally determined by using noncancerous human fibroblast cells.

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