67154-40-9 Usage
Uses
Used in Organic Synthesis:
N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a crosslinking agent for [creating covalent bonds between molecules], which is crucial in the development of new organic compounds and materials.
Used in Materials Science:
N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a component in the synthesis of advanced materials for [enhancing their properties through crosslinking].
Used in Biochemical Research:
N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a fluorescent labeling reagent for [tagging biomolecules to study their structure, function, and interactions], providing insights into biological processes.
Used in Biotechnological Applications:
N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a selective binder for [targeting thiol groups in proteins and peptides], facilitating the development of new biotechnological tools and techniques.
Used in Fluorescent Probes and Dyes Development:
N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a component in the creation of fluorescent probes and dyes for [imaging studies in biological and medical research], aiding in the visualization of cellular and molecular events.
Used in Imaging Studies:
In the field of Biological and Medical Research, N-(4-FLUORO-3-NITROPHENYL)MALEIMIDE is used as a fluorescent probe for [enhancing the visualization of biological processes and structures], contributing to a deeper understanding of disease mechanisms and potential therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 67154-40-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,5 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 67154-40:
(7*6)+(6*7)+(5*1)+(4*5)+(3*4)+(2*4)+(1*0)=129
129 % 10 = 9
So 67154-40-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H5FN2O4/c11-7-2-1-6(5-8(7)13(16)17)12-9(14)3-4-10(12)15/h1-5H
67154-40-9Relevant academic research and scientific papers
Potent Nematicidal Activity of Maleimide Derivatives on Meloidogyne incognita
Eloh, Kodjo,Demurtas, Monica,Mura, Manuel Giacomo,Deplano, Alessandro,Onnis, Valentina,Sasanelli, Nicola,Maxia, Andrea,Caboni, Pierluigi
, p. 4876 - 4881 (2016/07/06)
Different maleimide derivatives were synthesized and assayed for their in vitro activity on the soil inhabiting, plant-parasitic nematode Meloidogyne incognita, also known as root-knot nematode. The compounds maleimide, N-ethylmaleimide, N-isopropylmaleimide, and N-isobutylmaleimide showed the strongest nematicidal activity on the second stage juveniles of the root-knot nematode with EC50/72h values of 2.6 ± 1.3, 5.1 ± 3.4, 16.2 ± 5.4, and 19.0 ± 9.0 mg/L, respectively. We also determined the nematicidal activity of copper sulfate, finding an EC50 value of 48.6 ± 29.8 mg/L. When maleimide at 1 mg/L was tested in combination with copper sulfate at 50 mg/L, we observed 100% mortality of the nematodes. We performed a GC-MS metabolomics analysis after treating nematodes with maleimide at 8 mg/L for 24 h. This analysis revealed altered fatty acids and diglyceride metabolites such as oleic acid, palmitic acid, and 1-monopalmitin. Our results suggest that maleimide may be used as a new interesting building block for developing new nematicides in combination with copper salts.
