67159-43-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Pyrrolidinone, 3-methyl-4-phenylis used as a solvent for various pharmaceutical applications due to its ability to dissolve a wide range of compounds. Its solubility properties make it suitable for use in the formulation of drugs and drug delivery systems.
Used in Agricultural Industry:
In the agricultural sector, 2-Pyrrolidinone, 3-methyl-4-phenylserves as an intermediate in the synthesis of agrochemicals, including pesticides and herbicides. Its reactivity and functional groups facilitate the creation of effective compounds for crop protection and management.
Used in Industrial Applications:
2-Pyrrolidinone, 3-methyl-4-phenylis utilized as an intermediate in organic synthesis for the production of various industrial chemicals. Its unique structure allows for the development of new compounds with specific properties, such as improved performance or reduced environmental impact.
Used in Drug Discovery Research:
2-Pyrrolidinone, 3-methyl-4-phenylis employed as a building block in drug discovery research. Its chemical properties and structural features make it a promising candidate for the design and synthesis of new pharmaceutical compounds with potential therapeutic applications.
Overall, the diverse applications of 2-Pyrrolidinone, 3-methyl-4-phenylhighlight its importance in various industries, showcasing its potential as a versatile and valuable chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 67159-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,5 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67159-43:
(7*6)+(6*7)+(5*1)+(4*5)+(3*9)+(2*4)+(1*3)=147
147 % 10 = 7
So 67159-43-7 is a valid CAS Registry Number.
67159-43-7Relevant academic research and scientific papers
Tucker, John A.,Clayton, Terrance L.,Mordas, Donald M.
, p. 4370 - 4375 (1997)
The utility of nitroolefins as "+C-C-NH2" and "+C(C=O)R" synthons is limited by their facile polymerization in the presence of nucleophiles. Although a number of procedures have been developed for the successful alkylation of ketones with nitroolefins, currently available procedures for the corresponding reaction of esters suffer from important limitations such as modest yields, lack of demonstrated generality, inconveniently low reaction temperatures, and/or the use of a large excess of one of the two reactants. In the present work, we examined the efficacy of a series of Lewis acid catalysts for the alkylation of ketene silyl acetals with nitroolefins. Previously reported conditions using diisopropoxytitanium dichloride failed to give satisfactory results with nitroolefins lacking a substituent α to the NO2 group. In contrast, good to excellent results were obtained using sterically congested Lewis acids of the type pioneered by Yamamoto. The successful use of nitroethylene in this reaction represents a significant extension of the utility of this relatively unused "+CH2CH2NH2" synthon.
