67175-54-6Relevant academic research and scientific papers
Highly enantioselective proline-catalysed direct aldol reaction of chloroacetone and aromatic aldehydes
Martinez-Castaneda, Angel,Poladura, Belen,Rodriguez-Solla, Humberto,Concellon, Carmen,Del Amo, Vicente
supporting information; experimental part, p. 5188 - 5190 (2012/05/20)
Ready salted proline: The combination of proline and an achiral triazabicyclodecene-derived guanidinium salt permits, for the first time, the direct aldol reaction of chloroacetone and aromatic aldehydes (see scheme). The resulting chlorohydrins are formed with high regio-, diastereo- and enantioselectivity. This procedure is experimentally simple and green, working without solvent, in test tubes placed inside a standard laboratory fridge without agitation or mechanical stirring.
Kinetics of oxidation of styryl ketones by pyridinium chlorochromate
Mithula, M. Chandra,Murugesan, V.,Ananthakrishnanadar, P.
, p. 37 - 41 (2007/10/03)
The kinetics of oxidation of substituted styryl phenyl ketones and of substituted styryl methyl ketones by pyridinium chlorochromate (PCC) have been studied in 90percent acetic acid-10percent water (v/v) containing perchloric acid and NaClO4, at 30 deg, 40 deg, 50 deg and 60 deg C.The two reactions are first order each in ketones and PCC.The rate constants are well correlated with ?+ constants.The effects of varying and the percentage of acetic acid on the reaction rate have also been studied.A suitable mechanism has been proposed.
