67175-80-8Relevant academic research and scientific papers
Synthesis of cationic 1-substituted-dicarbonyl(η5-4- methoxycyclohexadienyl)-(triphenylphosphine)iron complexes
Guillou, Catherine,Millot, Nicolas,Reboul, Vincent,Thal, Claude
, p. 4515 - 4518 (1996)
Cationic 1-substituted-dicarbonyl(π5-4-methoxycyclohexadienyl)- (triphenylphosphine)iron complexes 10 form a new class of highly functionalised iron complexes which have never been described. They were obtained from neutral 1-substituted (πsup
First synthesis and reactivity of phosphinite and phosphine bridge chelate dicarbonyl (η5-4-methoxycyclohexadienyl)iron complexes
Millot, Nicolas,Guillou, Catherine,Thal, Claude
, p. 12553 - 12564 (1997)
Chelated dicarbonyl (η4-4-methoxycyclohexadiene) iron complexes 6 and 15 which possess a phosphinite and a phosphine bridge respectively form a new class of iron complexes. Their cations 5 and 16 reacted regioselectively with nucleophiles in go
Reductive cyclization strategy for construction of the highly oxygenated CD ring system of aconitine
Matsuzawa, Akinobu,Kasamatsu, Akihiko,Sugita, Kazuyuki
, p. 4585 - 4587 (2016)
The synthesis of a CD ring analogue of aconitine is described. The SmI2-mediated reductive cyclization of an α,β-epoxyketone with a pendant formyl group allowed for stereocontrolled construction of the bicyclo[3.2.1]octane framework. Further ox
Development of an efficient route toward meiogynin A-inspired dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins
Desrat, Sandy,Remeur, Camille,Roussi, Fanny
, p. 5520 - 5531 (2015/05/20)
The synthesis, on a large scale, with very good yield and er via an efficient strategy, of a chiral 4-substituted 2-cyclohexenone intermediate, was a milestone in the synthesis of seven analogues of meiogynin A, a natural sesquiterpenoid dimer. These comp
From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins
Desrat,Remeur,Gény,Rivière,Colas,Dumontet,Birlirakis,Iorga,Roussi
supporting information, p. 8593 - 8596 (2014/07/22)
The synthesis of one of the most potent dual inhibitors of the anti-apoptotic proteins Bcl-xL and Mcl-1 is reported. This analogue of a natural sesquiterpenoid dimer meiogynin A was elaborated by a convergent asymmetric synthesis with 36% yield in ten steps. the Partner Organisations 2014.
γ-turn peptidomimetics as fibrinogen antagonists
-
, (2008/06/13)
This invention relates to a method of inhibiting platelet aggregation, and compounds which are mimics of the peptide sequence Arg-Gly-Asp.
A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of γ-turn mimetics into a model substrate
Newlander,Callahan,Moore,Tomaszek Jr.,Huffman
, p. 2321 - 2331 (2007/10/02)
C7 mimetics, designed to lock three amino acid residues of a peptide chain into a γ-turn conformation, were introduced sequentially between the P3 to P2' positions of a model HIV-1 protease substrate I (resulting in compou
