671808-90-5Relevant academic research and scientific papers
Synthesis and photooxygenation of homochiral 2-methylpyrrole derivatives of chiral amino alcohols: Simple, selective access to chiral bicyclic lactams
Aydogan, Feray,Demir, Ayhan S.
, p. 259 - 265 (2007/10/03)
Homochiral 2-methylpyrrole derivatives are synthesized in high yields starting from chiral amino alcohols and 5-chloro-3-pentene-2-one. The photooxygenation of these compounds in the presence of a photosynthesizer furnishes the pyrrolooxazolone structures in high diastereoselectivities. In all of the examples, trans-isomers are formed as the major products.
