67191-20-2

Upstream product

• 110-91-8 morpholine 
• 10132-07-7 4-amino-2,6-dichloropyrimidine 

Downstream Products

• 1075215-67-6 [3-[[2-[(2,6-dimorpholin-4-yl-pyrimidin-4-yl)amino]pyrimidin-4-yl]-methyl-amino]-4-methyl-phenyl]methanol 

Relevant academic research and scientific papers

PYRIMIDINE DERIVATIVES 934

A compound of formula (I) where one of A1, A2 or A3 is N, and the others are independently selected from CH or N; ring B is a fused 5 or 6-membered carbocyclic or heterocyclic which is optionally substituted as defined in

N' - (PHENYL) -N- (MORPHOLIN-4-YL-PYRIDIN-2-YL) -PYRIMIDINE-2, 4-DIAMINE DERIVATIVES AS EPHB4 KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE CONDITIONS

The invention concerns pyrimidine com pounds of Formula (I), or a pharmaceutically acceptable salt thereof where A1, A2, A3, R1, n, R2, R3, and R4 are as defined in the descripti