67199-65-9

Basic information

• Product Name: Benzenemethanamine, 2-amino-4-chloro-
• CAS NO: 67199-65-9
• Molecular Formula: C7H9ClN2
• Molecular Weight: 156.615
• Mol File: 67199-65-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 302.0±27.0 °C(Predicted)
• Density: 1.266±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanamine, 2-amino-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, 2-amino-4-chloro-(67199-65-9)
• EPA Substance Registry System: Benzenemethanamine, 2-amino-4-chloro-(67199-65-9)

Safety Data

• Hazardous Substances Data: 67199-65-9(Hazardous Substances Data)

Upstream product

• 38487-86-4 2-amino-4-chlorobenzonitrile 

Downstream Products

• 1431959-31-7 N-(2-((3-((1H-pyrrolo[2,3-b]pyridin-4-yl)methyl)thioureido)methyl)-5-chlorophenyl)acrylamide trifluoroacetate 
• 1431959-33-9 N-(2-((3-((1H-pyrrolo[2,3-b]pyridin-4-yl)methyl)thioureido)methyl)-5-chlorophenyl)but-2-ynamide trifluoroacetate 
• 867164-87-2 7-chloro-2-phenylquinazoline 
• 69498-30-2 6-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole 
• 807640-42-2 5-hexenamide, N-[(2-amino-4-chlorophenyl)methyl]- 

Relevant articles and documents

Base-Promoted Synthesis of 2-Aryl Quinazolines from 2-Aminobenzylamines in Water

A transition-metal-free procedure for the synthesis of a highly valuable class of heteroaromatics, quinazolines, was developed by using easily available 2-aminobenzylamines and α,α,α-trihalotoluenes. The transformation proceeded smoothly in the presence of only sodium hydroxide and molecular oxygen in water at 100 °C, furnishing a variety of 2-aryl quinazolines. The crystallization process of the crude reaction mixture for the purification of the solid products circumvents huge solvent-consuming workup and column chromatographic techniques, which make the overall process more sustainable and economical.

Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position

Pyrrolidine(thi)one compounds substituted by heterocyclic substituents in the 3-position, their preparation and use in pharmaceutical compositions, in particular as immunomodulators for treatment and/or inhibition of inflammatory and autoimmune diseases and haematological-oncological diseases.