67218-92-2

Upstream product

• 67250-66-2 1-benzyl-5-benzyloxy-1H-imidazole-4-carboxylic acid amide 
• 3287-99-8 benzylamine hydrochloride 
• 67218-88-6 N-Benzyl-2-benzyloxycarbonylamino-malonamic acid ethyl ester 
• 67218-89-7 (Benzylcarbamoyl-carbamoyl-methyl)-carbamic acid benzyl ester 
• 67218-90-0 2-Amino-N-benzyl-malonamide 
• 122-51-0 orthoformic acid triethyl ester 

Relevant academic research and scientific papers

Studies on imidazole derivatives and related compounds. II. Characterization of substituted derivatives of 4-carbamoylimidazolium-5-olate by ultraviolet absorption spectra

The representative mono- and dialkyl-substituted derivatives of 4-carbamoylimidazolium-5-olate were synthesized unequivocally. On the basis of their spectral data from ultraviolet absorption spectra in acidic, basic and neutral solutions, we have found so

N-Substituted imidazolecarboxamide derivatives

N-Substituted imidazolecarboxamide compounds represented by the formula; STR1 wherein R1 is hydrogen atom, lower alkyl, lower alkenyl, aralkyl, R2 is hydrogen atom, lower alkyl, lower alkenyl, aralkyl, 1-adamantyl, R3 is hydrogen atom, lower alkyl, aralkyl; with the proviso that one of R1, R2 or R3 is not hydrogen when the other two are hydrogen, are produced by reacting aminomalonamide derivative with orthoformate derivative in high yields. The compounds (I) exhibit anti-tumor activity against experimental tumors such as Sarcoma 180 in mice.